日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell analysis identifies Ifi27l2a as a gene regulator of microglial inflammation in the context of aging and stroke in mice.

单细胞分析发现 Ifi27l2a 是小鼠衰老和中风背景下小胶质细胞炎症的基因调节因子

Kim Gab Seok, Harmon Elisabeth, Gutierrez Manuel C, Kim Sodam, Vance Lauren, Burrous Haven, Stephenson Jessica M, Chauhan Anjali, Banerjee Anik, Wise Zachary, Doan Andrea, Ahn John, Wu Ting, Bautista-Garrido Jesus, Lee Juneyoung, Tan Chunfeng, Jung Joo Eun, McCullough Louise D, Wythe Joshua D, Marrelli Sean P

Integrative single cell RNA and spatial profiling identify mechanisms of neonatal brain hemorrhage pathophysiology and repair

整合单细胞RNA和空间分析揭示新生儿脑出血病理生理和修复机制

Forero, Santiago A; Chen, Zhihua; Pirani, Ali; De, Arpan; Wise, Zachary; Zheng, Xiaofeng; Morales, John E; McCarty, Joseph H

Ifi27l2a acts as a cytokine that promotes a pro-inflammatory phenotype in microglia and enhances neuroinflammation.

Ifi27l2a 作为一种细胞因子,可促进小胶质细胞的促炎表型,并增强神经炎症。

Kim Sodam, Burrous Haven, Harmon Elisabeth, Vance Lauren, Wu Ting, Andersohn Alexander, Doan Andrea, Wolocko Darby, Wise Zachary, Kitamura Yuki, Jung Joo Eun, Colpo Gabriela, Couture Lucy, Blixt Frank, McCullough Louise, Marrelli Sean, Kim Gab Seok

Single Cell RNA Sequencing and Spatial Profiling Identify Mechanisms of Neonatal Brain Hemorrhage Development and Resolution.

单细胞 RNA 测序和空间分析揭示新生儿脑出血发生和消退的机制

Forero Santiago A, Chen Zhihua, Pirani Ali, De Arpan, Wise Zachary, Morales John E, McCarty Joseph H

Single-cell analysis identifies Ifi27l2a as a novel gene regulator of microglial inflammation in the context of aging and stroke.

单细胞分析发现 Ifi27l2a 是衰老和中风背景下小胶质细胞炎症的新型基因调节因子

Kim Gab Seok, Harmon Elisabeth, Gutierrez Manuel, Stephenson Jessica, Chauhan Anjali, Banerjee Anik, Wise Zachary, Doan Andrea, Wu Ting, Lee Juneyoung, Jung Joo Eun, McCullough Louise, Wythe Joshua, Marrelli Sean

RAE1ε ligand expressed on pancreatic islets recruits NKG2D receptor-expressing cytotoxic T cells independent of T cell receptor recognition

胰岛上表达的 RAE1ε 配体募集 NKG2D 受体表达细胞毒性 T 细胞,不依赖于 T 细胞受体识别

Mary A Markiewicz, Erica L Wise, Zachary S Buchwald, Amelia K Pinto, Biljana Zafirova, Bojan Polic, Andrey S Shaw

IL-12 enhances CTL synapse formation and induces self-reactivity

IL-12 增强 CTL 突触形成并诱导自身反应

Mary A Markiewicz, Erica L Wise, Zachary S Buchwald, Elizabeth E Cheney, Ted H Hansen, Anish Suri, Saso Cemerski, Paul M Allen, Andrey S Shaw