文献库，生知库 | 链接生命科学的每一步

Zhu, Yuan; Xiao, Xuewen; Liu, Yiliang; Wang, Zheng; Luo, Tengfei; Xu, Tianyan; Yang, Qijie; Hao, Xiaoli; Zhang, Cong; Zhang, Sizhe; Luo, Shilin; Zhou, Yafang; Liao, Xinxin; Tian, Yun; Weng, Ling; Fang, Liangjuan; Tang, Beisha; Jiao, Bin; Li, Jinchen; Shen, Lu

神经科学

发表日期：2026

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Multidimensional modeling of biological aging: integrating gait, eye movement, rest-state functional connectivity, and plasma biomarkers in non-dementia older adults

生物衰老的多维建模：整合非痴呆老年人的步态、眼动、静息态功能连接和血浆生物标志物

期刊:Jpad-Journal of Prevention of Alzheimers Disease

影响因子:7.8

doi:10.1016/j.tjpad.2026.100566

Lin, Jingyi; Liu, Yiliang; Ouyang, Ziyu; Yang, Xuan; Zhang, Sizhe; Xu, Tianyan; Yang, Qijie; Zhu, Yuan; Wan, Meidan; Xiao, Xuewen; Fan, Xiangmin; Tang, Beisha; Shen, Lu; Jiao, Bin; Luo, Shilin

衰老

发表日期：2026

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Development and validation of machine learning models with blood-based digital biomarkers for Alzheimer's disease diagnosis: a multicohort diagnostic study.

利用基于血液的数字生物标志物开发和验证机器学习模型以诊断阿尔茨海默病：一项多队列诊断研究

期刊:EClinicalMedicine

影响因子:10

doi:10.1016/j.eclinm.2025.103142

Jiao Bin, Ouyang Ziyu, Xiao Xuewen, Zhang Cong, Xu Tianyan, Yang Qijie, Zhu Yuan, Liu Yiliang, Liu Xixi, Zhou Yafang, Liao Xinxin, Luo Shilin, Tang Beisha, Li Zhigang, Shen Lu

其它

发表日期：2025

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Genetic risk and plasma biomarkers of dementia with Lewy bodies in a Chinese population

中国人群中路易体痴呆的遗传风险和血浆生物标志物

期刊:Npj Parkinsons Disease

影响因子:8.2

doi:10.1038/s41531-025-00988-z

Hao, Xiaoli; Xiao, Xuewen; Weng, Ling; Lin, Zhuojie; Xu, Qian; Du, Juan; Yang, Qijie; Zhu, Yuan; Liu, Yiliang; Xu, Tianyan; Zhou, Yafang; Liao, Xinxin; Guo, Jifeng; Luo, Shilin; Wang, Junling; Yan, Xinxiang; Tang, Beisha; Li, Jinchen; Jiao, Bin; Shen, Lu

发表日期：2025

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Evaluating the diagnostic performance of six plasma biomarkers for Alzheimer's disease and other neurodegenerative dementias in a large Chinese cohort

在一项大型中国人群队列研究中评估六种血浆生物标志物对阿尔茨海默病和其他神经退行性痴呆的诊断性能

期刊:Alzheimers Research & Therapy

影响因子:7.6

doi:10.1186/s13195-025-01712-y

Jiao, Bin; Ouyang, Ziyu; Liu, Yiliang; Zhang, Cong; Xu, Tianyan; Yang, Qijie; Zhang, Sizhe; Zhu, Yuan; Wan, Meidan; Xiao, Xuewen; Liu, Xixi; Zhou, Yafang; Liao, Xinxin; Zhang, Weiwei; Luo, Shilin; Tang, Beisha; Shen, Lu

A detection model of cognitive impairment via the integrated gait and eye movement analysis from a large Chinese community cohort

基于大型中国社区队列的步态和眼动综合分析的认知障碍检测模型

期刊:Alzheimers & Dementia

影响因子:11.1

doi:10.1002/alz.13517

Lin, Jingyi; Xu, Tianyan; Yang, Xuan; Yang, Qijie; Zhu, Yuan; Wan, Meidan; Xiao, Xuewen; Zhang, Sizhe; Ouyang, Ziyu; Fan, Xiangmin; Sun, Wei; Yang, Fan; Yuan, Li; Bei, Yuzhang; Wang, Junling; Guo, Jifeng; Tang, Beisha; Shen, Lu; Jiao, Bin

神经科学

发表日期：2024

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Genetic spectrum features and diagnostic accuracy of four plasma biomarkers in 248 Chinese patients with frontotemporal dementia

248例中国额颞叶痴呆患者的遗传谱特征及四种血浆生物标志物的诊断准确性

期刊:Alzheimers & Dementia

影响因子:11.1

doi:10.1002/alz.14215

Xu, Tianyan; Weng, Ling; Zhang, Cong; Xiao, Xuewen; Yang, Qijie; Zhu, Yuan; Zhou, Yafang; Liao, Xinxin; Luo, Shilin; Wang, Junling; Tang, Beisha; Jiao, Bin; Shen, Lu

发表日期：2024

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Integrated analysis of gut metabolome, microbiome, and brain function reveal the role of gut-brain axis in longevity

肠道代谢组、微生物组和脑功能的综合分析揭示了肠-脑轴在长寿中的作用

期刊:Gut Microbes

影响因子:11

doi:10.1080/19490976.2024.2331434

Jiao, Bin; Ouyang, Ziyu; Liu, Qianqian; Xu, Tianyan; Wan, Meidan; Ma, Guangrong; Zhou, Lu; Guo, Jifeng; Wang, Junling; Tang, Beisha; Zhao, Zhixiang; Shen, Lu

The associations of APP, PSEN1, and PSEN2 genes with Alzheimer's disease: A large case-control study in Chinese population

APP、PSEN1 和 PSEN2 基因与阿尔茨海默病的相关性：一项针对中国人群的大型病例对照研究

期刊:CNS Neuroscience & Therapeutics

影响因子:5

doi:10.1111/cns.13987

Xiao, Xuewen; Liu, Hui; Zhou, Lu; Liu, Xixi; Xu, Tianyan; Zhu, Yuan; Yang, Qijie; Hao, Xiaoli; Liu, Yingzi; Zhang, Weiwei; Zhou, Yafang; Wang, Junling; Li, Jinchen; Jiao, Bin; Shen, Lu; Liao, Xinxin

Mendelian randomization analyses of smoking and Alzheimer's disease in Chinese and Japanese populations

中国和日本人群吸烟与阿尔茨海默病之间的孟德尔随机化分析

期刊:Frontiers in Aging Neuroscience

影响因子:4.5

doi:10.3389/fnagi.2023.1157051

Zhu, Yuan; Guan, Ying; Xiao, Xuewen; Jiao, Bin; Liao, Xinxin; Zhou, Hui; Liu, Xixi; Qi, Feiyan; Peng, Qiyuan; Zhou, Lu; Xu, Tianyan; Yang, Qijie; Zhang, Sizhe; Li, Meng; Zhu, Zhouhai; Lu, Sheming; Li, Jinchen; Tang, Beisha; Shen, Lu; Yao, Jianhua; Zhou, Yafang

阿尔茨海默症

发表日期：2023

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Short tandem repeat expansions in patients with neurodegenerative dementia

神经退行性痴呆患者的短串联重复序列扩增

Multidimensional modeling of biological aging: integrating gait, eye movement, rest-state functional connectivity, and plasma biomarkers in non-dementia older adults

生物衰老的多维建模：整合非痴呆老年人的步态、眼动、静息态功能连接和血浆生物标志物

Development and validation of machine learning models with blood-based digital biomarkers for Alzheimer's disease diagnosis: a multicohort diagnostic study.

利用基于血液的数字生物标志物开发和验证机器学习模型以诊断阿尔茨海默病：一项多队列诊断研究

Genetic risk and plasma biomarkers of dementia with Lewy bodies in a Chinese population

中国人群中路易体痴呆的遗传风险和血浆生物标志物

Evaluating the diagnostic performance of six plasma biomarkers for Alzheimer's disease and other neurodegenerative dementias in a large Chinese cohort

在一项大型中国人群队列研究中评估六种血浆生物标志物对阿尔茨海默病和其他神经退行性痴呆的诊断性能

A detection model of cognitive impairment via the integrated gait and eye movement analysis from a large Chinese community cohort

基于大型中国社区队列的步态和眼动综合分析的认知障碍检测模型

Genetic spectrum features and diagnostic accuracy of four plasma biomarkers in 248 Chinese patients with frontotemporal dementia

248例中国额颞叶痴呆患者的遗传谱特征及四种血浆生物标志物的诊断准确性

Integrated analysis of gut metabolome, microbiome, and brain function reveal the role of gut-brain axis in longevity

肠道代谢组、微生物组和脑功能的综合分析揭示了肠-脑轴在长寿中的作用

The associations of APP, PSEN1, and PSEN2 genes with Alzheimer's disease: A large case-control study in Chinese population

APP、PSEN1 和 PSEN2 基因与阿尔茨海默病的相关性：一项针对中国人群的大型病例对照研究

Mendelian randomization analyses of smoking and Alzheimer's disease in Chinese and Japanese populations

中国和日本人群吸烟与阿尔茨海默病之间的孟德尔随机化分析