日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Optimizing drug design by merging generative AI with a physics-based active learning framework.

将生成式人工智能与基于物理的主动学习框架相结合,优化药物设计

Filella-Merce Isaac, Molina Alexis, Díaz Lucía, Orzechowski Marek, Berchiche Yamina A, Zhu Yang Ming, Vilalta-Mor Júlia, Malo Laura, Yekkirala Ajay S, Ray Soumya, Guallar Victor

Bortezomib-induced neuropathy is in part mediated by the sensitization of TRPV1 channels.

硼替佐米引起的神经病变部分是由 TRPV1 通道的敏化介导的

Sprague Jared M, Yekkirala Ajay S, Singh Bhagat, Tochitsky Ivan, Stephens Michael, Viramontes Octavio, Ivanis Jelena, Biscola Natalia P, Havton Leif A, Woolf Clifford J, Latremoliere Alban

An immunocytochemical-derived correlate for evaluating the bridging of heteromeric mu-delta opioid protomers by bivalent ligands

一种基于免疫细胞化学的相关性分析方法,用于评估二价配体对异源μ-δ阿片受体原体的桥接作用

Yekkirala, Ajay S; Kalyuzhny, Alexander E; Portoghese, Philip S

Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeys

临床上使用的阿片类镇痛药通过恒河猴体内的μ-δ阿片受体异聚体产生镇痛作用。

Yekkirala, Ajay S; Banks, Matthew L; Lunzer, Mary M; Negus, Stevens S; Rice, Kenner C; Portoghese, Philip S