日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Abnormal mechanical load aggravates subchondral bone remodeling and uneven tibial plateau settlement in knee osteoarthritis via activation of osteoblast Piezo1-Ca²⁺-JAK2/STAT3 signaling

异常机械负荷通过激活成骨细胞 Piezo1-Ca²⁺-JAK2/STAT3 信号通路，加剧膝骨关节炎中的软骨下骨重塑和胫骨平台不均匀沉降。

期刊:International Journal of Biological Sciences
影响因子:8.2
doi:10.7150/ijbs.124507.
Handi Li,Shuo Zhang,Chen Feng,Fangyan Cheng,Yuanyuan Han,Mengxue Wang,Shuai Zhou,Wenbo Shao,Wenzhong Chen,Jingguo Chen,Kai Liu,Yingze Zhang,Juan Wang
关节炎
信号转导
细胞生物学
炎症/感染
信号转导
JAK2
STAT3
ZO1
发表日期：2026
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Piezo1-driven mechanotransduction regulates mitochondrial biogenesis by AMPK/SIRT1-mediated PGC-1α deacetylation to ameliorate bone loss in disuse osteoporosis

Piezo1驱动的机械转导通过AMPK/SIRT1介导的PGC-1α去乙酰化调节线粒体生物合成，从而改善废用性骨质疏松症中的骨丢失。

期刊:International Journal of Biological Sciences
影响因子:8.2
doi:10.7150/ijbs.124043
Jianpeng Chen ，Dengying Wu ，Chengbin Huang ，Zijian Yan ，Jiahao Wang ，Siteng Li ，Xuankuai Chen ，Yanbin Zhu ，Yingze Zhang
表观遗传
骨质疏松
AMPK
SIRT1
PGC
乙酰化
线粒体
发表日期：2026
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Genetically Engineered Biomimetic Nanovesicles Co-Deliveing a Checkpoint Inhibitor and Doxorubicin for Enhanced Cancer Chemo-Immunotherapy

基因工程仿生纳米囊泡共递送检查点抑制剂和阿霉素以增强癌症化疗免疫疗法

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics18020159
Xing, Yunying; Liu, Xinyi; Wang, Zhenkun; Wang, Yingze; Zhang, Jing; Zhu, Wenxiang
Checkpoint
肿瘤
肿瘤免疫
囊泡
免疫/内分泌
发表日期：2026
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Nuclear farnesoid X receptor protects against bone loss by driving osteoblast differentiation through stabilizing RUNX2

核法尼醇X受体通过稳定RUNX2促进成骨细胞分化，从而防止骨质流失。

期刊:Bone Research
影响因子:14.3
doi:10.1038/s41413-024-00394-w
Qi Dong #,Haoyuan Fu #,Wenxiao Li #,Xinyu Ji,Yingchao Yin,Yiran Zhang,Yanbo Zhu,Guoqiang Li,Huiyang Jia,Heng Zhang,Haofei Wang,Jinglue Hu,Ganggang Wang,Zhihao Wu,Yingze Zhang,Sujuan Xu,Zhiyong Hou
细胞生物学
RUNX2
发表日期：2025
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3D-Printed Multidimensional Bionic Mg-MC/PLGA Composite for Tailored Repair of Segmental Long Bone Defects

用于定制修复节段性长骨缺损的3D打印多维仿生Mg-MC/PLGA复合材料

期刊:Advanced Healthcare Materials
影响因子:10
doi:10.1002/adhm.202501938.
Shihang Liu,Shuai Zhou,Tingting Zou,Guangzhao Hou,Qian Xiao,Lin Li,Jianjun Yang,Wei Chen,Yingze Zhang,Hongzhi Lv
3D/类器官
发表日期：2025
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Mechanical energy-charged navigating pump repair natural vascular scaffolds to reverse osteoporosis

机械能驱动的导航泵修复天然血管支架以逆转骨质疏松症

期刊:Materials Today Bio
影响因子:8.7
doi:10.1016/j.mtbio.2025.102431
Fengkun Wang ，Shuai Yang ，Yanbin Zhu ，Yiran Zhang ，Wei He ，Shuo Zhang ，Jiheng Xiao ，Chunxu Fu ，Peng Wang ，Jianpeng Chen ，Jiahao Wang ，Haiyune Zhao ，Wei Chen ，Yingze Zhang
心血管
骨质疏松
发表日期：2025
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Leptin receptor signaling mediates the distinct tendon-bone interface reconstruction in rotator cuff tears and osteoporosis-comorbid rotator cuff tears

瘦素受体信号传导介导肩袖撕裂和合并骨质疏松的肩袖撕裂中肌腱-骨界面重建的独特过程。

期刊:Stem Cell Research & Therapy
影响因子:7.1
doi:10.1186/s13287-025-04586-x
Dongxu Zhu,Xinrui Zhu,Yingze Zhang,Xiaohong Huang
骨质疏松
信号转导
发表日期：2025
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Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells

利用源自机械负荷启动间充质干细胞的双工程软骨细胞靶向细胞外囊泡治疗无细胞骨关节炎

期刊:Journal of Tissue Engineering
影响因子:6.7
doi:10.1177/20417314241312563
Peng Wang, Haiyue Zhao, Wei Chen, Yuhui Guo, Shuo Zhang, Xin Xing, Shuai Yang, Fengkun Wang, Juan Wang, Zengwu Shao, Yingze Zhang
发育与干细胞
关节炎
干细胞
发表日期：2025
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Biomechanical evaluation of the triangular support structure of the proximal femoral bionic nail compared to conventional long intramedullary nails for subtrochanteric fractures

对近端股骨仿生钉的三角形支撑结构与治疗股骨粗隆下骨折的传统长髓内钉进行生物力学评价

期刊:Frontiers in Bioengineering and Biotechnology
影响因子:4.8
doi:10.3389/fbioe.2025.1579842
Yang, Yanjiang; Wu, Dongwei; Cheng, Xiaodong; He, Wei; Chen, Wei; Zhang, Yingze; Zhang, Qi
骨折
发表日期：2025
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Biomechanical comparison of two fixation constructs for displaced quadrilateral surface acetabular fractures: a finite elements analysis

两种移位性四边形髋臼骨折固定结构的生物力学比较：有限元分析

期刊:BMC Musculoskeletal Disorders
影响因子:2.4
doi:10.1186/s12891-025-09351-y
Hou, Xi; Wang, Haofei; Liu, Zihan; Fu, Haoyuan; Hou, Zhiyong; Zhang, Yingze; Zhang, Ruipeng
骨折
发表日期：2025
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