Yoosu相关文献与解析，生知库 | 链接生命科学的每一步

Allogeneic DNT cell therapy synergizes with T cells to promote anti-leukemic activities while suppressing GvHD

同种异体DNT细胞疗法与T细胞协同作用，可促进抗白血病活性，同时抑制移植物抗宿主病（GvHD）。

期刊:Journal of Experimental & Clinical Cancer Research

Jongbok Lee ，Hyeonjeong Kang ，Branson Chen ，Yoosu Na ，Ismat Khatri ，Fraser Soares ，Housheng Hansen He ，Arjun D Law ，Tianzhong Pan ，Armin Gerbitz ，Xiaoyu Zhu ，Mark D Minden ，Li Zhang

Single-cell RNA sequencing of human double-negative T cells reveals a favorable cellular signature for cancer therapy

人类双阴性T细胞的单细胞RNA测序揭示了一种有利于癌症治疗的细胞特征。

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.6

doi:10.1136/jitc-2024-010684

Tin, Enoch; Khatri, Ismat; Fang, Karen; Na, Yoosu; Nawata, Michele; Arteaga, Juan; Minden, Mark D; Rutella, Sergio; Lee, Jongbok; Zhang, Li

Acute myeloid leukemia drug-tolerant persister cells survive chemotherapy by transiently increasing plasma membrane rigidity, that also increases their sensitivity to immune cell killing

急性髓系白血病耐药性持续细胞通过短暂增加细胞膜刚性来抵抗化疗，这种增加也会提高它们对免疫细胞杀伤的敏感性。

期刊:Haematologica

影响因子:7.9

doi:10.3324/haematol.2024.286018

Morgenstern, Yael; Lee, JongBok; Na, Yoosu; Lieng, Brandon Y; Ly, Nicholas S; Gwynne, William D; Hurren, Rose; Ma, Li; Ling, Dakai; Gronda, Marcela; Arruda, Andrea; Frisch, Avraham; Zuckerman, Tsila; Ofran, Yishai; Minden, Mark D; Zhang, Li; O'Brien, Catherine; Quaile, Andrew T; Montenegro-Burke, J Rafael; Schimmer, Aaron D

Double-negative T cells utilize a TNFα-JAK1-ICAM-1 cytotoxic axis against acute myeloid leukemia

双阴性 T 细胞利用 TNFα-JAK1-ICAM-1 细胞毒轴对抗急性髓系白血病

期刊:Blood Advances

影响因子:7.4

doi:10.1182/bloodadvances.2023011739

Enoch Tin, Jong Bok Lee, Ismat Khatri, Yoosu Na, Mark D Minden, Li Zhang

Targeting T-cell malignancies using allogeneic double-negative CD4-CAR-T cells

使用同种异体双阴性 CD4-CAR-T 细胞靶向治疗 T 细胞恶性肿瘤

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.3

doi:10.1136/jitc-2023-007277

Karen Kai-Lin Fang, Jongbok Lee, Ismat Khatri, Yoosu Na, Li Zhang

Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production

维奈托克通过增加活性氧（ROS）的产生来增强T细胞介导的抗白血病活性。

期刊:Blood

影响因子:21

doi:10.1182/blood.2020009081

Jong Bok Lee ，Dilshad H Khan ，Rose Hurren ，Mingjing Xu ，Yoosu Na ，Hyeonjeong Kang ，Sara Mirali ，Xiaoming Wang ，Marcela Gronda ，Yulia Jitkova ，Neil MacLean ，Andrea Arruda ，Zoe Alaniz ，Marina Y Konopleva ，Michael Andreeff ，Mark D Minden ，Li Zhang ，Aaron D Schimmer

Enhancing Therapeutic Efficacy of Double Negative T Cells against Acute Myeloid Leukemia Using Idelalisib

使用 Idelalisib 增强双阴性 T 细胞对急性髓系白血病的治疗效果

期刊:Cancers

影响因子:

doi:10.3390/cancers13205039

Hyeonjeong Kang, Jong Bok Lee, Ismat Khatri, Yoosu Na, Cheryl D'Souza, Andrea Arruda, Mark D Minden, Li Zhang

SOCS1 Protects Acute Myeloid Leukemia against Allogeneic T Cell-Mediated Cytotoxicity

SOCS1保护急性髓系白血病免受同种异体T细胞介导的细胞毒性作用

Allogeneic DNT cell therapy synergizes with T cells to promote anti-leukemic activities while suppressing GvHD

同种异体DNT细胞疗法与T细胞协同作用，可促进抗白血病活性，同时抑制移植物抗宿主病（GvHD）。

Single-cell RNA sequencing of human double-negative T cells reveals a favorable cellular signature for cancer therapy

人类双阴性T细胞的单细胞RNA测序揭示了一种有利于癌症治疗的细胞特征。

Acute myeloid leukemia drug-tolerant persister cells survive chemotherapy by transiently increasing plasma membrane rigidity, that also increases their sensitivity to immune cell killing

急性髓系白血病耐药性持续细胞通过短暂增加细胞膜刚性来抵抗化疗，这种增加也会提高它们对免疫细胞杀伤的敏感性。

Double-negative T cells utilize a TNFα-JAK1-ICAM-1 cytotoxic axis against acute myeloid leukemia

双阴性 T 细胞利用 TNFα-JAK1-ICAM-1 细胞毒轴对抗急性髓系白血病

Targeting T-cell malignancies using allogeneic double-negative CD4-CAR-T cells

使用同种异体双阴性 CD4-CAR-T 细胞靶向治疗 T 细胞恶性肿瘤

Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production

维奈托克通过增加活性氧（ROS）的产生来增强T细胞介导的抗白血病活性。

Enhancing Therapeutic Efficacy of Double Negative T Cells against Acute Myeloid Leukemia Using Idelalisib

使用 Idelalisib 增强双阴性 T 细胞对急性髓系白血病的治疗效果