Yu-Chian相关文献与解析，生知库 | 链接生命科学的每一步

Dual modality feature fused neural network integrating binding site information for drug target affinity prediction

双模态特征融合神经网络整合结合位点信息用于药物靶点亲和力预测

期刊:npj Digital Medicine

影响因子:15.1

doi:10.1038/s41746-025-01464-x

He, Haohuai; Chen, Guanxing; Tang, Zhenchao; Chen, Calvin Yu-Chian

发表日期：2025

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Multi-objective drug design with a scaffold-aware variational autoencoder

基于支架感知变分自编码器的多目标药物设计

期刊:Chemical Science

影响因子:7.4

doi:10.1039/d4sc08736d

Dong, Tiejun; You, Linlin; Chen, Calvin Yu-Chian

发表日期：2025

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CoupleMDA: Metapath-Induced Structural-Semantic Coupling Network for miRNA-Disease Association Prediction

CoupleMDA：基于元路径诱导的结构-语义耦合网络用于miRNA-疾病关联预测

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26104948

Li, Zhuojian; Chen, Guanxing; Tan, Guang; Chen, Calvin Yu-Chian

miRNA

发表日期：2025

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Using novel oxidative phosphorylation inhibitors to attenuate drug resistance in human gliomas

利用新型氧化磷酸化抑制剂减弱人类胶质瘤的耐药性

期刊:Excli Journal

影响因子:3.8

doi:10.17179/excli2025-8193

Chia-Kuang Tsai ,Chin-Yu Lin ,Yung-Lung Chang ,Fu-Chi Yang ,Chung-Hsing Chou ,Yu-Chian Huang ,Dueng-Yuan Hueng

Modal-nexus auto-encoder for multi-modality cellular data integration and imputation

用于多模态细胞数据集成和插补的模态联结自编码器

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-024-53355-6

Tang, Zhenchao; Chen, Guanxing; Chen, Shouzhi; Yao, Jianhua; You, Linlin; Chen, Calvin Yu-Chian

细胞生物学

发表日期：2024

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Scalable crystal structure relaxation using an iteration-free deep generative model with uncertainty quantification

利用无迭代深度生成模型实现可扩展的晶体结构弛豫及不确定性量化

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-024-52378-3

Yang, Ziduo; Zhao, Yi-Ming; Wang, Xian; Liu, Xiaoqing; Zhang, Xiuying; Li, Yifan; Lv, Qiujie; Chen, Calvin Yu-Chian; Shen, Lei

发表日期：2024

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De novo generation of SARS-CoV-2 antibody CDRH3 with a pre-trained generative large language model

使用预先训练的生成式大型语言模型从头生成 SARS-CoV-2 抗体 CDRH3

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-50903-y

Haohuai He #, Bing He #, Lei Guan #, Yu Zhao, Feng Jiang, Guanxing Chen, Qingge Zhu, Calvin Yu-Chian Chen, Ting Li, Jianhua Yao

AI empowering traditional Chinese medicine?

人工智能能否赋能传统中医？

期刊:Chemical Science

影响因子:7.4

doi:10.1039/d4sc04107k

Song, Zhilin; Chen, Guanxing; Chen, Calvin Yu-Chian

发表日期：2024

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Knowledge-based inductive bias and domain adaptation for cell type annotation

基于知识的归纳偏见和领域自适应用于细胞类型注释

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-024-07171-9

Tang, Zhenchao; Chen, Guanxing; Chen, Shouzhi; He, Haohuai; You, Linlin; Chen, Calvin Yu-Chian

细胞生物学

发表日期：2024

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A framework reforming personalized Internet of Things by federated meta-learning

通过联邦元学习改革个性化物联网的框架

Dual modality feature fused neural network integrating binding site information for drug target affinity prediction

双模态特征融合神经网络整合结合位点信息用于药物靶点亲和力预测

Multi-objective drug design with a scaffold-aware variational autoencoder

基于支架感知变分自编码器的多目标药物设计

CoupleMDA: Metapath-Induced Structural-Semantic Coupling Network for miRNA-Disease Association Prediction

CoupleMDA：基于元路径诱导的结构-语义耦合网络用于miRNA-疾病关联预测

Using novel oxidative phosphorylation inhibitors to attenuate drug resistance in human gliomas

利用新型氧化磷酸化抑制剂减弱人类胶质瘤的耐药性

Modal-nexus auto-encoder for multi-modality cellular data integration and imputation

用于多模态细胞数据集成和插补的模态联结自编码器

Scalable crystal structure relaxation using an iteration-free deep generative model with uncertainty quantification

利用无迭代深度生成模型实现可扩展的晶体结构弛豫及不确定性量化

De novo generation of SARS-CoV-2 antibody CDRH3 with a pre-trained generative large language model

使用预先训练的生成式大型语言模型从头生成 SARS-CoV-2 抗体 CDRH3

AI empowering traditional Chinese medicine?

人工智能能否赋能传统中医？

Knowledge-based inductive bias and domain adaptation for cell type annotation

基于知识的归纳偏见和领域自适应用于细胞类型注释