Engineering of CD8(+) T cells with an HIV-specific synthetic notch receptor to secrete broadly therapeutic antibodies for combining antiviral humoral and cellular immune responses.
利用 HIV 特异性合成 Notch 受体改造 CD8(+) T 细胞，使其分泌广谱治疗性抗体，从而结合抗病毒体液和细胞免疫反应
期刊:mBio
影响因子:4.7
doi:10.1128/mbio.03839-24
Meng Lina, Zhao Haichi, Chang Shangkun, Li Weiting, Tian Yinghui, Wang Ruihong, Wang Libian, Gu Tiejun, Wu Jiaxin, Yu Bin, Wang Chu, Yu Xianghui
