Elevated BICD2 DNA methylation in blood of major depressive disorder patients and reduction of depressive-like behaviors in hippocampal Bicd2-knockdown mice
重度抑郁症患者血液中BICD2 DNA甲基化水平升高,而海马Bicd2敲低小鼠的抑郁样行为减少。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2201967119
Xiu, Jianbo; Li, Jiayu; Liu, Zeyue; Wei, Hui; Zhu, Caiyun; Han, Rongrong; Liu, Zijing; Zhu, Wanwan; Shen, Yan; Xu, Qi
表观遗传
DNA甲基化
神经科学
抑郁症
CD2
BICD2