日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stable oxidative posttranslational modifications alter the gating properties of RyR1

稳定的氧化翻译后修饰改变RyR1的门控特性

Maarten M Steinz, Nicole Beard, Emily Shorter, Johanna T Lanner

FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells

FKBP12 是多发性骨髓瘤细胞中 ALK2 活性的主要调节剂

Ingrid Quist-Løkken, Clara Andersson-Rusch, Martin Haugrud Kastnes, Jürgen Markus Kolos, Jerome Jatzlau, Hanne Hella, Oddrun Elise Olsen, Anders Sundan, Petra Knaus, Felix Hausch, Toril Holien

Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively

调节诱导邻近靶向嵌合体 (RIPTAC):一种选择性杀死癌细胞的新型异双功能小分子治疗策略

Kanak Raina, Chris D Forbes, Rebecca Stronk, Jonathan P Rappi Jr, Kyle J Eastman, Samuel W Gerritz, Xinheng Yu, Hao Li, Amit Bhardwaj, Mia Forgione, Abigail Hundt, Madeline P King, Zoe M Posner, Allison Denny, Andrew McGovern, David E Puleo, Ethan Garvin, Rebekka Chenard, Nilesh Zaware, James J Mous

Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs)

磷酸化靶向嵌合体 (PhosTAC) 对磷蛋白活性的调节

Po-Han Chen, Zhenyi Hu, Elvira An, Ifunanya Okeke, Sijin Zheng, Xuanmeng Luo, Angela Gong, Saul Jaime-Figueroa, Craig M Crews

Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington's disease

钙调节缺陷在亨廷顿病心肺功能障碍中的作用

Haikel Dridi, Xiaoping Liu, Qi Yuan, Steve Reiken, Mohamad Yehia, Leah Sittenfeld, Panagiota Apostolou, Julie Buron, Pierre Sicard, Stefan Matecki, Jérome Thireau, Clement Menuet, Alain Lacampagne, Andrew R Marks

A chemical approach for global protein knockdown from mice to non-human primates

一种从小鼠到非人类灵长类动物的整体蛋白质敲低的化学方法

Xiuyun Sun #, Jun Wang #, Xia Yao #, Wen Zheng, Yang Mao, Tianlong Lan, Liguo Wang, Yonghui Sun, Xinyi Zhang, Qiuye Zhao, Jianguo Zhao, Rui-Ping Xiao, Xiuqin Zhang, Guangju Ji, Yu Rao

Ion channel gating in cardiac ryanodine receptors from the arrhythmic RyR2-P2328S mouse

心律失常 RyR2-P2328S 小鼠心脏兰尼碱受体的离子通道门控

Samantha C Salvage, Esther M Gallant, Nicole A Beard, Shiraz Ahmad, Haseeb Valli, James A Fraser, Christopher L-H Huang, Angela F Dulhunty

PCB 95 promotes dendritic growth in primary rat hippocampal neurons via mTOR-dependent mechanisms

PCB 95 通过 mTOR 依赖机制促进大鼠原代海马神经元树突生长

Kimberly P Keil, Galen W Miller, Hao Chen, Sunjay Sethi, Martin R Schmuck, Kiran Dhakal, Ji Won Kim, Pamela J Lein

The association between NFKB1 -94ATTG ins/del and NFKB1A 826C/T genetic variations and coronary artery disease risk

NFKB1 -94ATTG 插入/缺失和 NFKB1A 826C/T 基因变异与冠状动脉疾病风险之间的关联

Seidi, Abbas; Mirzaahmadi, Sina; Mahmoodi, Khalil; Soleiman-Soltanpour, Mohammad

Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway

营养短缺通过 GCN2-ATF4 信号通路触发己糖胺生物合成途径

Cédric Chaveroux, Carmen Sarcinelli, Virginie Barbet, Sofiane Belfeki, Audrey Barthelaix, Carole Ferraro-Peyret, Serge Lebecque, Toufic Renno, Alain Bruhat, Pierre Fafournoux, Serge N Manié