P53相关文献与解析，生知库 | 链接生命科学的每一步

Zhu Junkan, Ren Shencheng, Yi Yanjun, Wu Zhiyao, Lin Han, Shan Guangyao, Huang Xiaolong, Pan Binyang, Hu Zhengyang, Sui Qihai, Zhan Cheng, Wang Shuai, Liang Jiaqi

肿瘤

肺癌

P53

铁死亡

发表日期：2025

文献解析文献求助收藏

Combined TP53 status in tumor-free resection margins and circulating microRNA profiling predicts the risk of locoregional recurrence in head and neck cancer

肿瘤切缘阴性组织中TP53状态与循环microRNA谱的联合分析可预测头颈癌局部区域复发的风险。

期刊:Biomarker Research

影响因子:11.5

doi:10.1186/s40364-024-00576-y

Ganci, Federica; Allegretti, Matteo; Frascolla, Carlotta; Spinella, Francesca; Rollo, Francesca; Sacconi, Andrea; Valentina, Pascale De; Palcau, Alina Catalina; Manciocco, Valentina; Vescovo, Mariavittoria; Cotroneo, Ettore; Blandino, Francesca; Benevolo, Maria; Covello, Renato; Muti, Paola; Strano, Sabrina; Vidiri, Antonello; Fontemaggi, Giulia; Pellini, Raul; Blandino, Giovanni

Correction: Combined TP53 status in tumor-free resection margins and circulating microRNA profiling predicts the risk of locoregional recurrence in head and neck cancer

更正：肿瘤切缘阴性组织中TP53状态与循环microRNA谱分析相结合，可预测头颈癌局部区域复发的风险。

期刊:Biomarker Research

影响因子:11.5

doi:10.1186/s40364-024-00582-0

Ganci, Federica; Allegretti, Matteo; Frascolla, Carlotta; Spinella, Francesca; Rollo, Francesca; Sacconi, Andrea; De Pascale, Valentina; Palcau, Alina Catalina; Manciocco, Valentina; Vescovo, Mariavittoria; Cotroneo, Ettore; Blandino, Francesca; Benevolo, Maria; Covello, Renato; Muti, Paola; Strano, Sabrina; Vidiri, Antonello; Fontemaggi, Giulia; Pellini, Raul; Blandino, Giovanni

A patient with multiple primary malignant neoplasms with high variant allele frequencies of RB1, TP53, and TERT

一名患有多种原发性恶性肿瘤的患者，其RB1、TP53和TERT基因的变异等位基因频率较高。

期刊:Biomarker Research

影响因子:11.5

doi:10.1186/s40364-024-00567-z

Ma, Mingyang; Shang, Kun; Wang, Jiewei; Teng, Xiaojing; Li, Peng; Wang, Jing

Haploidentical CD7 CAR T-cells induced remission in a patient with TP53 mutated relapsed and refractory early T-cell precursor lymphoblastic leukemia/lymphoma

单倍体相合 CD7 CAR T 细胞诱导 TP53 突变复发难治性早期 T 细胞前体淋巴母细胞白血病/淋巴瘤患者病情缓解。

期刊:Biomarker Research

影响因子:11.5

doi:10.1186/s40364-022-00352-w

Dai, Hai-Ping; Cui, Wei; Cui, Qing-Ya; Zhu, Wen-Juan; Meng, Hui-Min; Zhu, Min-Qing; Zhu, Xia-Ming; Yang, Lin; Wu, De-Pei; Tang, Xiao-Wen

The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context

ATF2 对胃癌顺铂治疗反应的双面作用取决于 p53 环境

期刊:Cell and Bioscience

影响因子:6.1

doi:10.1186/s13578-022-00802-w

Lingxue Xu #, Jingjing Wang #, Danhua Zhang, Lijie Song, Han Wu, Jianyao Wang, Jinxin Miao, Haoran Guo, Sujuan Fang, Lingling Si, Jingfei Chen, Yifan Wu, Yangyang Wu, Lihong Wang, Na Zhang, Louisa Chard, Yaohe Wang, Zhenguo Cheng

The lncRNA TEX41 is upregulated in pediatric B-Cells Acute Lymphoblastic Leukemia and it is necessary for leukemic cell growth

lncRNA TEX41 在儿童 B 细胞急性淋巴细胞白血病中上调，并且是白血病细胞生长所必需的

期刊:Biomarker Research

影响因子:9.5

doi:10.1186/s40364-021-00307-7

Francesca Maria Orlandella #, Giovanni Smaldone #, Giuliana Salvatore, Luigi Vitagliano, Alessandra Cianflone, Rosanna Parasole, Giuliana Beneduce, Giuseppe Menna, Marco Salvatore, Peppino Mirabelli

Interaction between the microbiome and TP53 in human lung cancer

微生物组与TP53在人类肺癌中的相互作用

期刊:Genome Biology

影响因子:9.4

doi:10.1186/s13059-018-1501-6

Greathouse, K Leigh; White, James R; Vargas, Ashely J; Bliskovsky, Valery V; Beck, Jessica A; von Muhlinen, Natalia; Polley, Eric C; Bowman, Elise D; Khan, Mohammed A; Robles, Ana I; Cooks, Tomer; Ryan, Bríd M; Padgett, Noah; Dzutsev, Amiran H; Trinchieri, Giorgio; Pineda, Marbin A; Bilke, Sven; Meltzer, Paul S; Hokenstad, Alexis N; Stickrod, Tricia M; Walther-Antonio, Marina R; Earl, Joshua P; Mell, Joshua C; Krol, Jaroslaw E; Balashov, Sergey V; Bhat, Archana S; Ehrlich, Garth D; Valm, Alex; Deming, Clayton; Conlan, Sean; Oh, Julia; Segre, Julie A; Harris, Curtis C

A patient with newly diagnosed breast cancer found to have mosaic TP53 likely pathogenic variant

一名新确诊乳腺癌的患者被发现携带TP53嵌合型可能致病变异。

期刊:Ca-A Cancer Journal for Clinicians

影响因子:232.4

doi:10.3322/caac.70034

Mistry, Hetal D; Adams, MacKenzie R; Taneja, Charu; Massingham, Lauren J; Dibble, Elizabeth H; Leonard, Kara L; Hart, Jesse; Lagos, Galina G; Fenton, Mary Anne

Long-term follow-up demonstrates the curative potential of dual CD19/CD22 CAR-T-cell therapy alone or combined with autologous stem cell transplantation in TP53-altered relapsed/refractory B-cell non-Hodgkin lymphoma

长期随访结果表明，对于TP53改变的复发/难治性B细胞非霍奇金淋巴瘤，单独使用或联合自体干细胞移植的双重CD19/CD22 CAR-T细胞疗法具有治愈潜力。

期刊:Signal Transduction and Targeted Therapy

影响因子:52.7

doi:10.1038/s41392-025-02571-7

Mao, Zekai; Peng, Juan; Cao, Yang; Wang, Na; Wang, Jue; Yang, Yang; Xu, Jinghuan; Meng, Fankai; Chen, Liting; Mao, Xia; Guo, Jiaqi; Zhou, Xiaoxi; Zhang, Yicheng; Wei, Jia

ZNF146 accelerates lung adenocarcinoma progression through MDM2/p53 and PHGDH/ferroptosis.

ZNF146 通过 MDM2/p53 和 PHGDH/铁死亡加速肺腺癌的进展

Combined TP53 status in tumor-free resection margins and circulating microRNA profiling predicts the risk of locoregional recurrence in head and neck cancer

肿瘤切缘阴性组织中TP53状态与循环microRNA谱的联合分析可预测头颈癌局部区域复发的风险。

Correction: Combined TP53 status in tumor-free resection margins and circulating microRNA profiling predicts the risk of locoregional recurrence in head and neck cancer

更正：肿瘤切缘阴性组织中TP53状态与循环microRNA谱分析相结合，可预测头颈癌局部区域复发的风险。

A patient with multiple primary malignant neoplasms with high variant allele frequencies of RB1, TP53, and TERT

一名患有多种原发性恶性肿瘤的患者，其RB1、TP53和TERT基因的变异等位基因频率较高。

Haploidentical CD7 CAR T-cells induced remission in a patient with TP53 mutated relapsed and refractory early T-cell precursor lymphoblastic leukemia/lymphoma

单倍体相合 CD7 CAR T 细胞诱导 TP53 突变复发难治性早期 T 细胞前体淋巴母细胞白血病/淋巴瘤患者病情缓解。

The two-faced role of ATF2 on cisplatin response in gastric cancer depends on p53 context

ATF2 对胃癌顺铂治疗反应的双面作用取决于 p53 环境

The lncRNA TEX41 is upregulated in pediatric B-Cells Acute Lymphoblastic Leukemia and it is necessary for leukemic cell growth

lncRNA TEX41 在儿童 B 细胞急性淋巴细胞白血病中上调，并且是白血病细胞生长所必需的

Interaction between the microbiome and TP53 in human lung cancer

微生物组与TP53在人类肺癌中的相互作用

A patient with newly diagnosed breast cancer found to have mosaic TP53 likely pathogenic variant

一名新确诊乳腺癌的患者被发现携带TP53嵌合型可能致病变异。

Long-term follow-up demonstrates the curative potential of dual CD19/CD22 CAR-T-cell therapy alone or combined with autologous stem cell transplantation in TP53-altered relapsed/refractory B-cell non-Hodgkin lymphoma

长期随访结果表明，对于TP53改变的复发/难治性B细胞非霍奇金淋巴瘤，单独使用或联合自体干细胞移植的双重CD19/CD22 CAR-T细胞疗法具有治愈潜力。