PDK-1相关文献与解析，生知库 | 链接生命科学的每一步

PDK1 Inhibitor BX795 Improves Cisplatin and Radio-Efficacy in Oral Squamous Cell Carcinoma by Downregulating the PDK1/CD47/Akt-Mediated Glycolysis Signaling Pathway

PDK1 抑制剂 BX795 通过下调 PDK1/CD47/Akt 介导的糖酵解信号通路改善口腔鳞状细胞癌的顺铂和放射疗效

期刊:International Journal of Molecular Sciences

Shin Pai, Vijesh Kumar Yadav, Kuang-Tai Kuo, Narpati Wesa Pikatan, Chun-Shu Lin, Ming-Hsien Chien, Wei-Hwa Lee, Michael Hsiao, Shao-Chih Chiu, Chi-Tai Yeh, Jo-Ting Tsai

Copper Promotes Tumorigenesis by Activating the PDK1-AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner

铜以铜转运蛋白 1 依赖的方式激活 PDK1-AKT 致癌通路，促进肿瘤发生

期刊:Advanced Science

影响因子:

doi:10.1002/advs.202004303

Jianping Guo, Ji Cheng, Nana Zheng, Xiaomei Zhang, Xiaoming Dai, Linli Zhang, Changjiang Hu, Xueji Wu, Qiwei Jiang, Depei Wu, Hitoshi Okada, Pier Paolo Pandolfi, Wenyi Wei

Interleukin 1β-mediated HOXC10 Overexpression Promotes Hepatocellular Carcinoma Metastasis by Upregulating PDPK1 and VASP

白细胞介素1β介导的HOXC10过表达通过上调PDPK1和VASP促进肝细胞癌转移

期刊:Theranostics

影响因子:12.4

doi:10.7150/thno.41712

Yunzhi Dang, Jie Chen, Weibo Feng, Chenyang Qiao, Weili Han, Yongzhan Nie, Kaichun Wu, Daiming Fan, Limin Xia

MicroRNA‑363‑3p inhibits cell proliferation and induces apoptosis in retinoblastoma cells via the Akt/mTOR signaling pathway by targeting PIK3CA

MicroRNA‑363‑3p 通过靶向 PIK3CA，通过 Akt/mTOR 信号通路抑制视网膜母细胞瘤细胞增殖并诱导细胞凋亡

期刊:Oncology Reports

影响因子:3.8

doi:10.3892/or.2020.7544

Xiaojie Ma, Lan Jin, Xiaoqin Lei, Jingan Tong, Runsheng Wang

Sevoflurane preconditioning attenuates hypoxia/reoxygenation injury of H9c2 cardiomyocytes by activation of the HIF-1/PDK-1 pathway

七氟醚预处理通过激活 HIF-1/PDK-1 通路减轻 H9c2 心肌细胞的缺氧/复氧损伤。

期刊:PeerJ

影响因子:2.3

doi:10.7717/peerj.10603

Tianliang Hou # ,Haiping Ma # ,Haixia Wang ,Chunling Chen ,Jianrong Ye ,Ahmed Mohamed Ahmed ,Hong Zheng

Expression of PDK-1 and DMBT1 in the thyroid carcinoma and its clinicopathological significance

PDK-1和DMBT1在甲状腺癌中的表达及其临床病理意义

期刊:Oncology Letters

影响因子:2.2

doi:10.3892/ol.2019.10639

Sun, Zhichao; Xu, Lei

IGF-1 protects SH-SY5Y cells against MPP(+)-induced apoptosis via PI3K/PDK-1/Akt pathway

IGF-1通过PI3K/PDK-1/Akt通路保护SH-SY5Y细胞免受MPP(+)诱导的细胞凋亡。

期刊:Endocrine Connections

影响因子:2.8

doi:10.1530/EC-17-0350

Kim, Chanyang; Park, Seungjoon

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas

PI3K/AKT/mTOR通路激活对头颈部鳞状细胞癌患者预后的影响

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.8957

Darío García-Carracedo, Maria Ángeles Villaronga, Saúl Álvarez-Teijeiro, Francisco Hermida-Prado, Iñigo Santamaría, Eva Allonca, Laura Suárez-Fernández, Maria Victoria Gonzalez, Milagros Balbín, Aurora Astudillo, Pablo Martínez-Camblor, Gloria H Su, Juan Pablo Rodrigo, Juana María García-Pedrero

Helicobacter pylori modulates host cell survival regulation through the serine-threonine kinase, 3-phosphoinositide dependent kinase 1 (PDK-1)

幽门螺杆菌通过丝氨酸/苏氨酸激酶 3-磷酸肌醇依赖性激酶 1 (PDK-1) 调节宿主细胞存活。

期刊:BMC Microbiology

影响因子:4.2

doi:10.1186/s12866-015-0543-0

King, Charles C; Obonyo, Marygorret

Cooperative activation of PDK1 and AKT by MAPK4 enhances cancer growth and resistance to therapy

MAPK4 协同激活 PDK1 和 AKT 可增强癌症生长和治疗耐药性

PDK1 Inhibitor BX795 Improves Cisplatin and Radio-Efficacy in Oral Squamous Cell Carcinoma by Downregulating the PDK1/CD47/Akt-Mediated Glycolysis Signaling Pathway

PDK1 抑制剂 BX795 通过下调 PDK1/CD47/Akt 介导的糖酵解信号通路改善口腔鳞状细胞癌的顺铂和放射疗效

Copper Promotes Tumorigenesis by Activating the PDK1-AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner

铜以铜转运蛋白 1 依赖的方式激活 PDK1-AKT 致癌通路，促进肿瘤发生

Interleukin 1β-mediated HOXC10 Overexpression Promotes Hepatocellular Carcinoma Metastasis by Upregulating PDPK1 and VASP

白细胞介素1β介导的HOXC10过表达通过上调PDPK1和VASP促进肝细胞癌转移

MicroRNA‑363‑3p inhibits cell proliferation and induces apoptosis in retinoblastoma cells via the Akt/mTOR signaling pathway by targeting PIK3CA

MicroRNA‑363‑3p 通过靶向 PIK3CA，通过 Akt/mTOR 信号通路抑制视网膜母细胞瘤细胞增殖并诱导细胞凋亡

Sevoflurane preconditioning attenuates hypoxia/reoxygenation injury of H9c2 cardiomyocytes by activation of the HIF-1/PDK-1 pathway

七氟醚预处理通过激活 HIF-1/PDK-1 通路减轻 H9c2 心肌细胞的缺氧/复氧损伤。

Expression of PDK-1 and DMBT1 in the thyroid carcinoma and its clinicopathological significance

PDK-1和DMBT1在甲状腺癌中的表达及其临床病理意义

IGF-1 protects SH-SY5Y cells against MPP(+)-induced apoptosis via PI3K/PDK-1/Akt pathway

IGF-1通过PI3K/PDK-1/Akt通路保护SH-SY5Y细胞免受MPP(+)诱导的细胞凋亡。

Impact of PI3K/AKT/mTOR pathway activation on the prognosis of patients with head and neck squamous cell carcinomas

PI3K/AKT/mTOR通路激活对头颈部鳞状细胞癌患者预后的影响

Helicobacter pylori modulates host cell survival regulation through the serine-threonine kinase, 3-phosphoinositide dependent kinase 1 (PDK-1)

幽门螺杆菌通过丝氨酸/苏氨酸激酶 3-磷酸肌醇依赖性激酶 1 (PDK-1) 调节宿主细胞存活。