LPO相关文献与解析，生知库 | 链接生命科学的每一步

A NaV1.8FlpO mouse enabling selective intersectional targeting of low threshold C fiber mechanoreceptors and nociceptors

NaV1.8FlpO 小鼠能够选择性地交叉靶向低阈值 C 纤维机械感受器和伤害感受器

期刊:Frontiers in Molecular Neuroscience

影响因子:3.5

doi:10.3389/fnmol.2025.1574219

John C Y Chen ,Lech Kaczmarczyk ,Walker S Jackson ,Max Larsson

Case of maternal uniparental isodisomy with autosomal recessive Alport syndrome combined with congenital myasthenia and Oguchi disease

一例母系单亲同源二体性合并常染色体隐性遗传Alport综合征、先天性重症肌无力和Oguchi病的病例报告。

期刊:CEN Case Reports

影响因子:1

doi:10.1007/s13730-025-00972-9.

Misaki Akiyama ,Keiko Matsubara ,Hiroshi Terashima ,Yuichi Abe ,Kinji Ohno ,Koichi Kamei

LPO

发表日期：2025

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Targeting corticotropin-releasing hormone receptor type 1 (Crhr1) neurons: validating the specificity of a novel transgenic Crhr1-FlpO mouse

靶向促肾上腺皮质激素释放激素受体1型（Crhr1）神经元：验证新型转基因Crhr1-FlpO小鼠的特异性

期刊:Brain Structure & Function

影响因子:2.7

doi:10.1007/s00429-024-02879-0

Mason Hardy ,Yuncai Chen ,Tallie Z Baram ,Nicholas J Justice

Anti-microRNA-21 Therapy on Top of ACE Inhibition Delays Renal Failure in Alport Syndrome Mouse Models

在ACE抑制剂的基础上联合抗microRNA-21疗法可延缓Alport综合征小鼠模型的肾衰竭

期刊:Cells

影响因子:5.1

doi:10.3390/cells11040594

Diana Rubel ,Joseph Boulanger ,Florin Craciun ,Ethan Y Xu ,Yanqin Zhang ,Lucy Phillips ,Michelle Callahan ,William Weber ,Wenping Song ,Nicholas Ngai ,Nikolay O Bukanov ,Xingyi Shi ,Ali Hariri ,Hervé Husson ,Oxana Ibraghimov-Beskrovnaya ,Shiguang Liu ,Oliver Gross

Mouse

发表日期：2022

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Generation of a DAT-P2A-Flpo mouse line for intersectional genetic targeting of dopamine neuron subpopulations

构建DAT-P2A-Flpo小鼠品系，用于多巴胺神经元亚群的交叉基因靶向治疗

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2021.109123

Daniel J Kramer,Erin E Aisenberg,Polina Kosillo,Drew Friedmann,David A Stafford,Angus Yiu-Fai Lee,Liqun Luo,Dirk Hockemeyer,John Ngai,Helen S Bateup

Carvedilol and exercise combination therapy improves systolic but not diastolic function and reduces plasma osteopontin in Col4a3-/- Alport mice

卡维地洛联合运动疗法可改善Col4a3-/- Alport小鼠的收缩功能（而非舒张功能），并降低其血浆骨桥蛋白水平。

期刊:American Journal of Physiology-Heart and Circulatory Physiology

影响因子:4.1

doi:10.1152/ajpheart.00535.2020

Julian C Dunkley ,Camila I Irion ,Keyvan Yousefi ,Serene A Shehadeh ,Guerline Lambert ,Krista John-Williams ,Keith A Webster ,Jeffrey J Goldberger ,Lina A Shehadeh

发表日期：2021

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Generation of a conditional Flpo/FRT mouse model expressing constitutively active TGFβ in fibroblasts

构建成纤维细胞中组成型表达活性TGFβ的条件性Flpo/FRT小鼠模型

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-020-60272-3

Victoire Cardot-Ruffino ，Véronique Chauvet ，Cassandre Caligaris ，Adrien Bertrand-Chapel ，Nicolas Chuvin ，Roxane M Pommier ，Ulrich Valcourt ，David F Vincent ，Sylvie Martel ，Sophie Aires ，Bastien Kaniewski ，Pierre Dubus ，Philippe Cassier ，Stéphanie Sentis # ，Laurent Bartholin #

ColPortal, an integrative multiomic platform for analysing epigenetic interactions in colorectal cancer

ColPortal，一个用于分析结直肠癌表观遗传相互作用的整合多组学平台

期刊:Scientific Data

影响因子:5.8

doi:10.1038/s41597-019-0198-z

Angel Esteban-Gil ,Fernando Pérez-Sanz ,José García-Solano ,Begoña Alburquerque-González ,María Antonia Parreño-González ,María Del Carmen Legaz-García ,Jesualdo Tomás Fernández-Breis ,Edith Rodriguez-Braun ,Paola Pimentel ,Anne Tuomisto ,Markus Mäkinen ,Ondrej Slaby ,Pablo Conesa-Zamora

A novel mouse model for X-linked Alport syndrome induced by splicing mutation in the Col4a5 gene

一种由Col4a5基因剪接突变诱发的X连锁Alport综合征的新型小鼠模型

A NaV1.8FlpO mouse enabling selective intersectional targeting of low threshold C fiber mechanoreceptors and nociceptors

NaV1.8FlpO 小鼠能够选择性地交叉靶向低阈值 C 纤维机械感受器和伤害感受器

Case of maternal uniparental isodisomy with autosomal recessive Alport syndrome combined with congenital myasthenia and Oguchi disease

一例母系单亲同源二体性合并常染色体隐性遗传Alport综合征、先天性重症肌无力和Oguchi病的病例报告。

Targeting corticotropin-releasing hormone receptor type 1 (Crhr1) neurons: validating the specificity of a novel transgenic Crhr1-FlpO mouse

靶向促肾上腺皮质激素释放激素受体1型（Crhr1）神经元：验证新型转基因Crhr1-FlpO小鼠的特异性

Anti-microRNA-21 Therapy on Top of ACE Inhibition Delays Renal Failure in Alport Syndrome Mouse Models

在ACE抑制剂的基础上联合抗microRNA-21疗法可延缓Alport综合征小鼠模型的肾衰竭

Generation of a DAT-P2A-Flpo mouse line for intersectional genetic targeting of dopamine neuron subpopulations

构建DAT-P2A-Flpo小鼠品系，用于多巴胺神经元亚群的交叉基因靶向治疗

Carvedilol and exercise combination therapy improves systolic but not diastolic function and reduces plasma osteopontin in Col4a3-/- Alport mice

卡维地洛联合运动疗法可改善Col4a3-/- Alport小鼠的收缩功能（而非舒张功能），并降低其血浆骨桥蛋白水平。

Generation of a conditional Flpo/FRT mouse model expressing constitutively active TGFβ in fibroblasts

构建成纤维细胞中组成型表达活性TGFβ的条件性Flpo/FRT小鼠模型

ColPortal, an integrative multiomic platform for analysing epigenetic interactions in colorectal cancer

ColPortal，一个用于分析结直肠癌表观遗传相互作用的整合多组学平台