CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition
CREBBP失活使B细胞急性淋巴细胞白血病对BCL2抑制引起的铁死亡更加敏感
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-59531-6
Alicia Garcia-Gimenez ,Jonathan E Ditcham ,Dhoyazan M A Azazi ,George Giotopoulos ,Ryan Asby ,Eshwar Meduri ,Jaana Bagri ,Nathalie Sakakini ,Cecile K Lopez ,Nisha Narayan ,Tumas Beinortas ,Shuchi Agrawal-Singh ,Kent Fung ,David O'Connor ,Marc R Mansour ,Husam B R Alabed ,Benjamin Jenkins ,Albert Koulman ,Michael P Murphy ,Sarah J Horton ,Brian J P Huntly ,Simon E Richardson
信号转导
细胞生物学
白血病
BCL2
CREBBP
铁死亡