Anti-ATF6 antibody (Ab37149)
Cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 alpha, Activating transcription factor 6 alpha, ATF6-alpha, ATF6
详细信息
特异性
Based on 100% sequence alignment, this antibody detects ATF6 isoform A (alpha). The antibody is predicted to recognize the 50kDa fragment as it recognizes a peptide sequence from near the amino terminus. We have not tested stressed cells to see if the 50kDa cleavage product can be detected.
背景信息
What is this antibody validated in? Anti-ATF6 antibody (ab37149) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human, Mouse, Rat samples. What is the molecular weight of ATF6? Anti-ATF6 (ab37149) specifically detects a band for ATF6 (UniProt: P18850) at a molecular weight of 75kDa. Trusted by the scientific community Anti-ATF6 (ab37149) was first used in a scientific publication in 2006 and has been cited over 100 times in peer-reviewed journals. Reviewed by scientists Anti-ATF6 (ab37149) has over 5 independent reviews from customers. Specificity confirmed The specificity of Anti-ATF6 antibody (ab37149) has been confirmed by Western blot testing in ATF6 Knockout HeLa cells.
文献引用 (103)
Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR-Mediated Control of Immunoglobulin Homeostasis in Hybridomas.
定量蛋白质组学和 CRISPR/Cas9 编辑揭示了 UPR 介导的杂交瘤免疫球蛋白稳态控制。
Qiangjing Tablets modulate oxidative stress and endoplasmic reticulum stress through the PI3K/Akt/NRF-2 signaling axis and regulate gut microbiota in ornidazole-induced asthenozoospermia rats.
强经片通过 PI3K/Akt/NRF-2 信号轴调节氧化应激和内质网应激，并调节奥硝唑诱导的弱精子症大鼠的肠道菌群。
Astragaloside IV alleviates septic myocardial injury through DUSP1-Prohibitin 2 mediated mitochondrial quality control and ER-autophagy.
黄芪甲苷 IV 通过 DUSP1-Prohibitin 2 介导的线粒体质量控制和内质网自噬减轻脓毒症心肌损伤。
Macrophage ATF6 accelerates corticotomy-assisted orthodontic tooth movement through promoting Tnfα transcription
巨噬细胞ATF6通过促进Tnfα转录来加速皮质骨切开术辅助的正畸牙齿移动。
Changes in the endoplasmic reticulum‑mitochondria communication in dermal fibroblasts from early‑stage bipolar disorder patients: Skin‑brain axis as a new route to understand the pathophysiology of mental illness?
早期双相情感障碍患者真皮成纤维细胞内质网-线粒体通讯的变化：皮肤-脑轴是理解精神疾病病理生理学的新途径吗？
Piperlongumine Inhibits Lung Cancer Growth by Inducing Endoplasmic Reticulum Stress Leading to Suppression of M2 Macrophage Polarization.
胡椒碱通过诱导内质网应激抑制M2巨噬细胞极化，从而抑制肺癌生长
The Effects of Da-Chai-Hu Decoction Alleviating Pancreatic Exocrine Dysfunction by Inhibiting Endoplasmic Reticulum Stress of Acinar Cell in Mice with Chronic Pancreatitis.
大柴胡汤通过抑制慢性胰腺炎小鼠腺泡细胞内质网应激缓解胰腺外分泌功能障碍的作用。
Endoplasmic reticulum stress contributes to insulin resistance in Hashimoto's thyroiditis.
内质网应激是桥本甲状腺炎患者出现胰岛素抵抗的原因之一
Activation of TRIM37 by ATF6 and degradation of ACSL4: inhibiting ferroptosis and propelling cervical cancer progression.
ATF6 激活 TRIM37 并降解 ACSL4：抑制铁死亡并促进宫颈癌进展
Knockdown of JunB alleviates LPS-induced H9C2 cardiomyocyte injury and sepsis-induced myocardial injury by activating the PI3K/Akt/mTOR signaling pathway.
敲除 JunB 可激活 PI3K/Akt/mTOR 信号通路，从而减轻 LPS 诱导的 H9C2 心肌细胞损伤和脓毒症诱导的心肌损伤。
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