Anti-Calreticulin antibody - ER Marker (Ab2907)
CRTC, CALR, Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, HACBP, grp60, ERp60
详细信息
背景信息
Anti-Calreticulin antibody - ER Marker (ab2907) is a rabbit polyclonal antibody and is validated for use in ICC/IF, WB in human, mouse, rat samples. Anti-Calreticulin antibody - ER Marker (ab2907) has been cited over 256 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Calreticulin antibody - ER Marker (ab2907) has high sensitivity and specificity. Anti-Calreticulin antibody - ER Marker (ab2907) has 16 independent reviews from customers. Anti-Calreticulin antibody - ER Marker (ab2907) specifically detects Calreticulin (UniProt ID: P27797; Molecular weight: 46kDa) and is sold in 100 µL selling sizes. Calreticulin (CALR, HACBP) is a multifunctional protein involved in protein folding and calcium homeostasis within the endoplasmic reticulum. In oncology, it plays a crucial role in immunogenic cell death by acting as a signal for immune cells to target and destroy cancer cells. Calreticulin (CALR, HACBP) is also implicated in tumor progression and metastasis due to its role in cell adhesion and migration. As a result, it is being explored as a potential therapeutic target for cancer treatment.
文献引用 (254)
A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID.
独特的单核细胞转录状态将全身免疫失调与新冠肺炎长期症状中的肺功能损害联系起来。
Defining the reference proteomes for small extracellular vesicles and non-vesicular components.
确定小细胞外囊泡和非囊泡成分的参考蛋白质组。
Binary mineral nanoparticles enable intravascular delivery of metal ions to tumors for metalloimmunotherapy.
二元矿物纳米颗粒能够将金属离子通过血管输送到肿瘤，用于金属免疫疗法。
Boron neutron capture therapy preserves immune cells and induces robust anti-tumour immunity in preclinical mouse model.
硼中子俘获疗法可在临床前小鼠模型中保护免疫细胞并诱导强大的抗肿瘤免疫力。
Iodine-125 brachytherapy triggers immunogenic cell death and potentiates anti-PD-L1 immunotherapy in bone metastatic triple-negative breast cancer.
碘-125近距离放射疗法可触发免疫原性细胞死亡，并增强抗PD-L1免疫疗法在骨转移性三阴性乳腺癌中的疗效。
Nintedanib enhances the antitumor efficacy of pd-1 blockade, potentially through inhibition of myeloid-derived suppressor cells and cancer-associated fibroblasts.
尼达尼布可增强 PD-1 阻断的抗肿瘤疗效，其作用机制可能是抑制髓系来源的抑制细胞和癌症相关成纤维细胞。
Integrated Bioinformatics and Experimental Validation Reveal Fuzheng Yi'ai Formula Induces Immunogenic Cell Death Via the PERK-eIF2α-ATF4 Pathway for Prostate Cancer Treatment.
生物信息学与实验验证揭示扶正益爱方通过 PERK-eIF2α-ATF4 通路诱导免疫原性细胞死亡，用于治疗前列腺癌。
Inhibition of CDK1 Promotes Immunogenic Cell Death in Neuroblastoma.
CDK1抑制剂促进神经母细胞瘤的免疫原性细胞死亡。
Immunogenic Tumor Cell Death Induced by Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer: An Immunohistochemical Analysis.
新辅助化疗诱导肌层浸润性膀胱癌患者免疫原性肿瘤细胞死亡：免疫组织化学分析。
STING agonist-based ER-targeting molecules boost antigen cross-presentation
基于STING激动剂的ER靶向分子可增强抗原交叉呈递
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