Anti-CD19 antibody [EPR23174-145] (Ab245235)

CD19, B-lymphocyte antigen CD19, Differentiation antigen CD19, Cd19

反应种属:Mouse
抗原名称:CD19
应用:WB, IHC, FCM, IF/ICC, MIHC, IP

用户验证的应用

推荐稀释比例

  • IHC-P1/1000
  • mIHC1/1000
  • WB1/1000
  • ICC/IF1/50
  • Flow Cyt1/500
  • IP1/30
  • IHC-Fr1/250

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-CD19 antibody [EPR23174-145]
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification Protein A

背景信息

Anti-CD19 antibody [EPR23174-145] (ab245235) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB, mIHC in mouse samples. Anti-CD19 antibody [EPR23174-145] (ab245235) has been cited over 21 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-CD19 antibody [EPR23174-145] (ab245235) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-CD19 antibody [EPR23174-145] (ab245235) has 4 independent reviews from customers. Anti-CD19 antibody [EPR23174-145] (ab245235) specifically detects CD19 (UniProt ID: P25918; Molecular weight: 58kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR23174-145 - ab267394. Antibody clone EPR23174-145 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, APC, PE, Alexa Fluor® 647 ( ab270176, ab270178, ab306537, ab314289 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (66)

IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma.

IFNγ依赖性代谢重编程抑制黑色素瘤中不成熟的、促转移的淋巴状态。

In vivo multiplexed modeling reveals diverse roles of the TBX2 subfamily and Egr1 in Kr as-driven lung adenocarcinoma.

体内多重建模揭示了 TBX2 亚家族和 Egr1 在 Kr 驱动的肺腺癌中的多种作用。

Khalil Athar, Dinh Trang, Parks Meaghan, Obeng Rebecca C, Gryder Berkley, Kresak Adam, Wang Yuxiang, Maltas Jeff, Bedrock Madeline, Wei Xiangzhen, Faber Zachary, Rahm Mira, Scott Jacob, LaFramboise Thomas, Wang Zhenghe, McFarland Christopher

Telomere damage enhances immunogenicity of neuroblastoma and accelerates response to anti-PD-L1 treatment.

端粒损伤增强神经母细胞瘤的免疫原性,并加速对PD-L1抗体治疗的反应。

Höppner Stefanie, Werr Lisa, Szilagyi Beata, Bartenhagen Christoph, Hellmann Anna-Maria, Rosswog Carolina, Linden Emma, Primke Gerrit, Kahlert Yvonne, Ibruli Nadliv, Hemstedt Nadine, Lorenz Witali, Brägelmann Johannes, Hölzel Michael, Fischer Matthias

Macrophage-derived CCL20 promotes abdominal aortic aneurysm progression via lymphocytes CCR6.

巨噬细胞衍生的 CCL20 通过淋巴细胞 CCR6 促进腹主动脉瘤的进展。

Mucosal B Cell Expansion and Maturation Contribute to Colitis Pathogenesis.

黏膜B细胞的扩增和成熟是结肠炎发病机制的促成因素。

Fung Ivan C N, Koelink Pim J, Mulders Lieven G M, Admiraal Iris, Verseijden Caroline, Verhoeff Jan, Wildenberg Manon E, Luo Yi, D'Haens Geert R, Li Yim Andrew Y F, de Jonge Wouter J

TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function

TCF1 和 LEF1 促进 B-1a 细胞稳态和调节功能

Qian Shen ,Hao Wang # ,Jonathan A Roco # ,Xiangpeng Meng # ,Marita Bosticardo ,Marie Hodges ,Michael Battaglia ,Zhi-Ping Feng ,Benjamin James Talks ,Jason Powell ,Vijaya Baskar Mahalingam Shanmugiah ,Julia Chu ,Najib M Rahman ,Alguili Elsheikh ,Probir Chakravarty ,Amalie Grenov ,Max Emmerich ,Ottavia M Delmonte ,Alexandra F Freeman ,Michael D Keller ,Brahim Belaid ,Ilenia Papa ,James C Lee ,Pablo F Cañete ,Paula Gonzalez-Figueroa ,Yaoyuan Zhang ,Hai-Hui Xue ,Samra Turajlic ,Luigi D Notarangelo ,Muzlifah Haniffa ,Lee Ann Garrett-Sinha ,Helen M Parry ,Nikolaos I Kanellakis ,Carola G Vinuesa

Inhibiting B cells enhances the efficacy of STING agonism or immune checkpoint blockade in hepatocellular carcinoma

抑制B细胞可增强STING激动剂或免疫检查点阻断剂在肝细胞癌中的疗效

Xin Liu # ,Zelong Liu # ,Chengzhan Zhu # ,Tatsuya Kobayashi ,Pin-Ji Lei ,Yue Shi ,Dandan Yuan ,Jianguo Wang ,Min Li ,Aya Matsui ,Kassiana Mafra ,Tomofumi Ando ,Ken Kojo ,Rieke Schleinhege ,Kento Miyazaki ,Peigen Huang ,Ming Kuang ,Lloyd Bod ,Dan G Duda

A UFD1 variant encoding a microprotein modulates UFD1f and IPMK ubiquitination to play pivotal roles in anti-stress responses

UFD1 变体编码一种微蛋白,该变体调节 UFD1f 和 IPMK 的泛素化,从而在抗应激反应中发挥关键作用。

Xiuzhi Li # ,Xiaolin Wang # ,Xu Liu ,Ge Shan ,Liang Chen

Combination LIGHT overexpression and checkpoint blockade disrupts the tumor immune environment impacting colorectal liver metastases.

LIGHT 过表达与检查点阻断相结合会破坏肿瘤免疫环境,从而影响结直肠肝转移。

Keenan Bridget P, Qiao Guilin, Kunda Nicholas, Kone Lyonell, Guldberg Sophia M, Todeschini Letizia, Kumar Prabhakaran, Pollini Tommaso, Hernandez Sophia, Qin Jianzhong, Fong Lawrence, Spitzer Matthew H, Prabhakar Bellur S, Maker Ajay V

Exploring the role of readthrough-inducing molecule 2,6-diaminopurine to increase immune response against cancer cells.

探索通读诱导分子 2,6-二氨基嘌呤在增强抗癌细胞免疫反应中的作用。

Sandoval Pacheco Carmen, Leroy Alice M, Derhourhi Mehdi, Cardon Tristan, Leroy Catherine, Jouy Nathalie, Com Emmanuelle, Guevel Blandine, Bourette Roland, Carrard Julie, Barros Daniela, Duchêne Belinda, Toussaint Bénédicte, Froguel Philippe, Jonckheere Nicolas, Chassat Thierry, Van Seuningen Isabelle, Lavigne Régis, Pineau Charles, Pierre Philippe, Soncin Fabrice, Salzet Michel, Bonnefond Amélie, Lejeune Fabrice
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