Anti-GRP78 BiP antibody [EPR4041(2)] (Ab108615)

GRP78, HSPA5, Endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein, Binding-immunoglobulin protein, Heat shock protein 70 family protein 5, Heat shock protein family A member 5, Immunoglobulin heavy chain-binding protein, GRP-78, BiP, HSP70 family protein 5

反应种属:Human, Mouse, Rat
抗原名称:HSPA5
应用:WB, IHC, FCM

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Stable for 12 months at -20°C
无载体蛋白No

特异性

Stimulation may be required to allow detection of the target protein due to low levels of endogenous expression in some samples. Please see images below for recommended treatment conditions and positive controls. The mouse and rat recommendation is based on the WB results. We do not guarantee IHC-P for mouse and rat.

背景信息

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (95)

TIGAR regulates intestinal mucus barrier integrity by inhibiting lactylation of G6PD/6PGD in ulcerative colitis.

TIGAR 通过抑制溃疡性结肠炎中 G6PD/6PGD 的乳酸化来调节肠道粘液屏障的完整性。

Wu Dan, Su Sen, Zhang Panyang, Zha Xule, Wei Yan, Zhang Ting, Liu Xiaoyan, Chen Qian, Li Chunyan, Huang Qianying, Zhou Zhihao, Yang Yan, Xia Lin, Fan Shijun, Peng Xi

ATF5-Dependent GDF15 Expression Mediates Anesthesia-Induced Neuroprotection Against Stroke.

ATF5依赖的GDF15表达介导麻醉诱导的抗中风神经保护作用。

Ju Xianshu, Zhang Tao, Cui Jianchen, Lee Yulim, Lee Suho, Kim Ho Min, Hong Boohwi, Park Jiho, Choi Chul Hee, Yi Hyon-Seung, Heo Jun Young, Chung Woosuk

GATA2 deficiency exacerbates chronic liver injury via disrupting hepatocyte death-regeneration balance: Clinical, histopathological, and molecular evidence.

GATA2 缺乏通过破坏肝细胞死亡-再生平衡加剧慢性肝损伤:临床、组织病理学和分子证据。

Chen Yun-Fen, Li Su-Qun, Zhang Jing, Ma Wen-Ting, Zhou Ying, Rao Jian-Xu, Yi Yu, Cheng Qi-Jiao, Zhong Wei-Wei, Chen Huan, Chen Ying-Hua, Luo Ya-Wen, He Yi-Huai

Enhanced Early Detection of Colorectal Cancer via Blood Biomarker Combinations Identified Through Extracellular Vesicle Isolation and Artificial Intelligence Analysis

通过细胞外囊泡分离和人工智能分析鉴定的血液生物标志物组合,可增强结直肠癌的早期检测。

Bonhan Koo,Young Il Kim,Minju Lee,Seok-Byung Lim,Yong Shin

Impaired RelA signaling and lipid metabolism dysregulation in hepatocytes: driving forces in the progression of metabolic dysfunction-associated steatotic liver disease

肝细胞中 RelA 信号受损和脂质代谢失调:代谢功能障碍相关脂肪肝进展的驱动力

Yihuai He, Jinlian Jiang, Lili Ou, Yunfen Chen, Aikedaimu Abudukeremu, Guimei Chen, Weiwei Zhong, Zhigang Jiang, Nuerbiye Nuermaimaiti, Yaqun Guan

Unveiling MiR-3085-3p as a modulator of cartilage degeneration in facet joint osteoarthritis: A novel therapeutic target

揭示 MiR-3085-3p 作为小关节骨关节炎软骨退化的调节剂:一种新的治疗靶点

Zhong-Ming Lai, Cheng-Long Li, Jun-Xiong Zhang, Xiang Ao, Cheng-Shuo Fei, Xin Xiang, Yan-Lin Chen, Ze-Sen Chen, Rui-Qian Tan, Liang Wang, Zhong-Min Zhang

Hesperetin induces apoptosis in lung squamous carcinoma cells via G(2)/M cycle arrest, inhibition of the Notch1 pathway and activation of endoplasmic reticulum stress.

橙皮苷通过 G(2)/M 周期阻滞、抑制 Notch1 通路和激活内质网应激诱导肺鳞状细胞癌细胞凋亡

Xie Qianlong, He Ziming, Tan Lingfang, Li Min, Zhuang Min, Liu Chen, Chen Sunhui, Jin Long, Sui Yuxia

Bletilla striata polysaccharides alleviate metabolic dysfunction-associated steatotic liver disease through enhancing hepatocyte RelA/ HNF1α signaling

白芨多糖通过增强肝细胞 RelA/HNF1α 信号传导缓解代谢功能障碍相关的脂肪肝

Yi-Huai He, Li-Li Ou, Jin-Lian Jiang, Yun-Fen Chen, Aikedaimu Abudukeremu, Yuan Xue, Mao-Yuan Mu, Wei-Wei Zhong, De-Lin Xu, Xuan-Yu Meng, Ya-Qun Guan

USP8 inhibits cigarette smoke extract combined with LPS-induced inflammatory response and ER stress by regulating the ABCB1-mediated MAPK signaling pathway in human bronchial epithelial cells.

USP8 通过调节人支气管上皮细胞中 ABCB1 介导的 MAPK 信号通路,抑制香烟烟雾提取物与 LPS 诱导的炎症反应和内质网应激。

Wang Meng, Song Weipeng, Liu Xiaoming, Meng Aihong

miR-1275 Delivered via Mesenchymal Stem Cell-Derived Extracellular Vesicles Regulates ER-Phagy Through AXIN2 in Nucleus Pulposus Cells

miR-1275通过间充质干细胞来源的细胞外囊泡递送,并通过髓核细胞中的AXIN2调节内质网吞噬作用。

Zhiwu Dong,Hailong Zhang,Wenwei Yang,Keliang Huang,Xin Zhang,Lianxiang Xing,Ying Zhang,Kewen Zhao
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10