Anti-ACE2 antibody [EPR4435(2)] (Ab108252)

UNQ868/PRO1885, ACE2, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, Angiotensin-converting enzyme-related carboxypeptidase, Metalloprotease MPROT15, ACEH, ACE-related carboxypeptidase

反应种属:Human, Mouse, Rat
抗原名称:ACE2
应用:WB, IHC, ELISA, IP

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

What is this antibody validated in? Anti-ACE2 antibody [EPR4435(2)] (ab108252) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), ELISA in Human, Mouse, Rat samples. What is the molecular weight of ACE2? Anti-ACE2 [EPR4435(2)] (ab108252) specifically detects a band for ACE2 (UniProt: Q9BYF1) at a molecular weight of 92kDa. Trusted by the scientific community Anti-ACE2 [EPR4435(2)] (ab108252) was first used in a scientific publication in 2011 and has been cited over 150 times in peer-reviewed journals. Reviewed by scientists Anti-ACE2 [EPR4435(2)] (ab108252) has over 10 independent reviews from customers. Specificity confirmed The specificity of Anti-ACE2 antibody [EPR4435(2)] (ab108252) has been confirmed by Western blot testing in ACE2 Knockout HepG2 cell line, ab273733. Other related products We have a range of other formats of antibody clone [EPR4435(2)] also available for your convenience: ab108252, Carrier free - ab239924, Alexa Fluor ® 647 - ab311135, Alexa Fluor ® 594 - ab311772, Alexa Fluor ® 555 - ab313253, Alexa Fluor ® 488 - ab317075 Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (177)

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Activation of Angiotensin-Converting Enzyme 2 Mitigates Gastrointestinal Acute Radiation Syndrome.

激活血管紧张素转换酶 2 可减轻胃肠道急性放射综合征。

Sharma Guru Prasad, Nissen Austen, Gasperetti Tracy, Foeckler Jamie, Frei Anne C, Kuehn Rachel, Gerhartz Melany, Heinzelman Pete, Romero Philip A, Zenga Joseph, Himburg Heather A

SARS-CoV-2 Nsp15 facilitates immune evasion and viral replication by limiting multiple host innate immune pathways, including cGAS-STING.

SARS-CoV-2 Nsp15 通过限制多种宿主先天免疫途径(包括 cGAS-STING)来促进免疫逃避和病毒复制。

Chiu Hsin-Ping, Yeo Yao Yu, Lai Tsoi Ying, Hung Chuan-Tien, Kowdle Shreyas, Haas Griffin D, Jiang Sizun, Sun Weina, Lee Benhur

ACE2 expression by colonic epithelial cells is associated with viral infection, immunity, and energy metabolism.

结肠上皮细胞表达ACE2与病毒感染、免疫和能量代谢有关。

Qi Yuyin, Huang Yuxin, Chen Hanhan, Li Jie, Liu Ming, Xiong Wenjing, Tang Qin, Zhang Yuxia

Automated Label-Free Assay for Viral Detection and Inhibitor Screening via Biomembrane-Functionalized Microelectrode Arrays.

利用生物膜功能化微电极阵列进行病毒检测和抑制剂筛选的自动化无标记检测。

Lu Zixuan, Treiber Jeremy, Kallitsis Konstantinos, Selivanovitch Ekaterina, Wheeler Alexandra, Lopez-Cavestany Maria, Chao Zhongmou, Barron Sarah L, Park Ju An, Hoven Darius, Scheeder Anna, Withers Aimee, Hess Becky M, Kaminski Clemens F, Salleo Alberto, Pappa Anna-Maria, Daniel Susan, Owens Róisín M

SARS-CoV-2 Productively Infects Human Hepatocytes and Induces Cell Death

SARS-CoV-2 有效感染人类肝细胞并诱导细胞死亡

Chunkyu Ko, Cho-Chin Cheng, Daniele Mistretta, Shubhankar Ambike, Julia Sacherl, Stoyan Velkov, Bo-Hung Liao, Romina Bester, Merve Gültan, Olga Polezhaeva, Alexander Herrmann, Constanze A Jakwerth, Carsten B Schmidt-Weber, Joachim J Bugert, Roman Wölfel, Vincent Grass, Sandra Essbauer, Daniel Schnep

Integrated multi‑omics analysis of liver metabolic dysregulation in ACE2 knockout mice.

ACE2 基因敲除小鼠肝脏代谢紊乱的多组学综合分析

Xiao Shuai, Guo Jinxiu, Yu Bo, Zhao Shiyuan, Shang Yicun, Li Ni, Cui Jiyao, Song Fangqiang, Jiang Pei

Optimized gene transduction in human lung organoids: A high-efficiency method for advanced research applications

人类肺类器官中基因转导的优化:一种用于高级研究应用的高效方法

Jasmin Khateeb #, Jady Liang #, Yuchong Li, Thenuka Thanabalasingam, Julie Khang, Mirjana Jerkic, Giovanna Pellecchia, Bhooma Thiruv, Ya-Wen Chen, Ori Rotstein, Arthur S Slutsky, Haibo Zhang2

Expression of the Renin-Angiotensin System in the Heart, Aorta, and Perivascular Adipose Tissue in an Animal Model of Type 1 Diabetes.

1 型糖尿病动物模型中心脏、主动脉和血管周围脂肪组织中肾素-血管紧张素系统的表达。

Martín-Carro Beatriz, Fernández-Villabrille Sara, Calvó-García Paula, González-García Nerea, Baena-Huerta Francisco, Hospital-Sastre Angie, Pujante Pedro, López-Hernández Francisco José, Naves-Díaz Manuel, Panizo Sara, Carrillo-López Natalia, Alonso-Montes Cristina, Fernández-Martín José Luis

Immunohistochemical Analysis of Placental Tissue of Women Infected with SARS-CoV-2 During Pregnancy-A Prospective Clinical Study.

妊娠期感染SARS-CoV-2妇女胎盘组织的免疫组织化学分析——一项前瞻性临床研究

Bicanin Ilic Marija, Nikolic Turnic Tamara, Nikolov Aleksandar, Mujkovic Srdjan, Likic Ladjevic Ivana, Ilic Igor, Spasojevic Marija, Jovic Nikola, Joksimovic Jovic Jovana, Rakic Dejana, Ahmetovic Begzudin, Rosic Sara, Dimitrijevic Aleksandra
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