Anti-Osteopontin antibody (Ab8448)
BNSP, OPN, PSEC0156, SPP1, Osteopontin, Bone sialoprotein 1, Nephropontin, Secreted phosphoprotein 1, Urinary stone protein, Uropontin, SPP-1
详细信息
特异性
Osteopontin is directed against human osteopontin. The antibody recognizes the full-length osteopontin protein (which runs at 66 kDa on westerns), as well as the C-terminal fragments of both thrombin and MMP-cleaved OPN. The 32 kDa MMP-cleaved C-fragment is recognized, but not the 40 kDa N-terminal fragment. Reactivity is reported to occur with osteopontin from swine, dog, mouse and rat.
背景信息
Product Specifications Anti-Osteopontin antibody (ab8448) is a rabbit polyclonal antibody and is validated for use in IHC-P in human samples. Anti-Osteopontin antibody (ab8448) specifically detects Osteopontin (UniProt ID: P10451; Molecular weight: 34kDa) and is sold in 200 µL selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-Osteopontin antibody (ab8448) has high sensitivity and specificity. Anti-Osteopontin antibody (ab8448) has been cited over 445 times in peer reviewed journals and is trusted by the scientific community. Anti-Osteopontin antibody (ab8448) has 14 independent reviews from customers.
文献引用 (414)
Hepatic Arterial Flow-Induced Portal Tract Fibrosis in Portal Hypertension: The Role of VCAM-1 and Osteopontin-Expressing Macrophages.
肝动脉血流诱导门静脉高压中的门静脉区纤维化：VCAM-1 和表达骨桥蛋白的巨噬细胞的作用。
Pharmacological Enhancement of Integrated Stress Response Confers Protection in Calcific Aortic Valve Disease.
药物增强综合应激反应可对钙化性主动脉瓣疾病起到保护作用。
Decoding muscle-resident Schwann cell dynamics during neuromuscular junction remodeling.
解码神经肌肉接头重塑过程中肌肉驻留雪旺细胞的动态变化。
Involvement of c-Myc/WWP1/TRIM65 Axis in Renal Fibrosis.
c-Myc/WWP1/TRIM65轴参与肾纤维化。
Therapeutic potency and the related mechanism of deinoxanthin in experimental animal and cell models of periodontitis.
去氧黄素在牙周炎动物和细胞模型中的治疗效力及相关机制。
Pulsed radiofrequency therapy ameliorates steroid-induced osteonecrosis of the femoral head by promoting nerve growth factor production.
脉冲射频疗法通过促进神经生长因子的产生来改善类固醇引起的股骨头坏死。
Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer's disease
小胶质细胞机制驱动阿尔茨海默病免疫患者体内β-淀粉样蛋白的清除
Mutations in the human CSF1R gene impact microglia's maintenance of brain white matter integrity.
人类 CSF1R 基因的突变会影响小胶质细胞维持大脑白质完整性的功能
Oriented Cortical-Bone-Like Silk Protein Lamellae Effectively Repair Large Segmental Bone Defects in Pigs
定向皮质骨样丝蛋白片层有效修复猪大段骨缺损
Single-cell sequencing reveals a senescent immune landscape in bone marrow lesions inducing articular cartilage damage in osteoarthritis.
单细胞测序揭示了骨髓病变中衰老的免疫环境，这种环境会导致骨关节炎中的关节软骨损伤。
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