Anti-TSG101 antibody [EPR7130(B)] (Ab125011)
Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101
用户验证的应用
推荐稀释比例
- IHC-P1/300 For unpurified use at 1/30. Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
- WB1/1000 - 1/10000
- ICC/IF1 µg/mL For unpurified use at 1/10. This product gave a positive signal in HeLa fixed with 100% methanol (5 min).
- Flow Cyt (Intra)1/20 For unpurified use at 1/3. ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
详细信息
背景信息
Anti-TSG101 antibody [EPR7130(B)] (ab125011) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB. Anti-TSG101 antibody [EPR7130(B)] (ab125011) was first used in a scientific publication in 2014 and has been cited over 603 times in peer reviewed journals. It's performance in Western Blot in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-TSG101 antibody [EPR7130(B)] (ab125011) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-TSG101 antibody [EPR7130(B)] (ab125011) has 10 independent reviews from customers. Anti-TSG101 antibody [EPR7130(B)] (ab125011) specifically detects TSG101 (UniProt ID: Q99816; Molecular weight: 44kDa) and is sold in a convenient trial size to enable initial testing (10 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR7130(B) - ab207567. Antibody clone EPR7130(B) is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, PE, Alexa Fluor ® 555, APC ( ab207663, ab207664, ab209927, ab214404, ab316299 ). Tumor Susceptibility Gene 101 (TSG101) is involved in the endosomal sorting complex required for transport (ESCRT) pathway, which is crucial for cellular processes like vesicle trafficking and degradation. Alterations in TSG101 expression are linked to various cancers, including breast cancer and glioblastoma, where it can act as both a tumor suppressor and an oncoprotein depending on the context. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (1095)
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生物工程改造的细胞外囊泡可逃避溶酶体降解,并将 Tet-PKM2 递送至巨噬细胞进行免疫代谢重编程,用于治疗牙周炎。
A dual-functional engineered exosome-laden hydrogel redirects endogenous neural stem cell fate for spinal cord injury repair.
一种双功能工程化外泌体负载水凝胶可改变内源性神经干细胞的命运,用于脊髓损伤修复。
Multifunctional extracellular vesicles inhibiting autophagy ameliorate immunotherapy in non-small cell lung cancer.
抑制自噬的多功能细胞外囊泡可改善非小细胞肺癌的免疫治疗。
Magnetic-Assisted Aptamer Selection and Isolation of Migrasomes for Application in Lung Adenocarcinoma Proteomic Analysis.
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Activating the Osteoblastic USP26 Pathway Alleviates Multi-Organ Fibrosis by Decreasing Insulin Resistance.
激活成骨细胞 USP26 通路可通过降低胰岛素抵抗来缓解多器官纤维化。
Mitochondrial protein-enriched artificial nanovesicles: mitochondrial recovery and antioxidation for diabetic wound treatment.
富含线粒体蛋白的人工纳米囊泡:用于糖尿病伤口治疗的线粒体恢复和抗氧化作用。
Programmable iPSC-derived CAR-NK vesicles remodel the immune microenvironment and eradicate tumors
可编程的iPSC衍生CAR-NK囊泡重塑免疫微环境并根除肿瘤
Exercise-primed exosomes in an injectable hydrogel promote myocardial repair via angiogenesis and ferroptosis inhibition.
注射式水凝胶中的运动预处理外泌体通过血管生成和抑制铁死亡促进心肌修复。
Co-delivery of panobinostat and siSTAT3 using engineered M1 exosomes to establish a one-two punch therapeutic strategy for glioblastoma recurrence.
利用工程化的 M1 外泌体共同递送帕比司他和 siSTAT3,建立治疗胶质母细胞瘤复发的双重打击疗法。
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