Anti-Caspase-3 antibody (Ab13847)
CPP32, CASP3, Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, CPP-32, SCA-1
详细信息
特异性
Stimulation is required to allow detection of the 17kDa cleaved form of the protein. Please see images below for recommended treatment conditions and positive controls.ab13847 recognizes a cleaved form of Caspase 3 (~17 kDa) after apoptosis has been induced in wildtype cells and not Caspase 3 knockout cells. Some customers have used this antibody successfully in IHC-P however our latest tests were unsuccessful and therefore we can no longer guarantee this application. We would recommend ab32351 and ab184787 as an alternative product for this application.
背景信息
Anti-Caspase-3 antibody (ab13847) is a rabbit polyclonal antibody and is validated for use in WB in human samples. Anti-Caspase-3 antibody (ab13847) has been cited over 1194 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Caspase-3 antibody (ab13847) has high sensitivity and specificity. The specificity of Anti-Caspase-3 antibody (ab13847) has been confirmed by testing in knockout samples. Anti-Caspase-3 antibody (ab13847) has 53 independent reviews from customers. Anti-Caspase-3 antibody (ab13847) specifically detects Caspase-3 (UniProt ID: P42574; Molecular weight: 17kDa) and is sold in 100 µg selling sizes.
文献引用 (997)
Roles of blood monocytes carrying TREM2R47H mutation in pathogenesis of Alzheimer's disease and its therapeutic potential in APP/PS1 mice
携带TREM2R47H突变的血液单核细胞在阿尔茨海默病发病机制中的作用及其在APP/PS1小鼠中的治疗潜力
Aβ -induced excessive mitochondrial fission drives type H blood vessels injury to aggravate bone loss in APP/PS1 mice with Alzheimer's diseases
Aβ 诱导的线粒体过度裂变导致 H 型血管损伤加剧阿尔茨海默病 APP/PS1 小鼠的骨质流失
Structural and Functional Characterization of the Aorta in Hypertrophic Obstructive Cardiomyopathy
肥厚型梗阻性心肌病主动脉的结构和功能特征
CHEK1 is a synthetic lethal interactor of FBXO7 in colonic epithelial cells.
CHEK1 是结肠上皮细胞中 FBXO7 的合成致死相互作用因子
Stroke in Pregnancy Brings Epigenetic Changes in Correlation with Affected Mitochondrial Dynamics and Inflammasome Mediated Apoptosis in Rodents.
妊娠期中风引起表观遗传变化，与啮齿动物线粒体动力学受损和炎症小体介导的细胞凋亡相关
Hypoxia Promotes the In Vitro Proliferation of Buffalo Spermatogonial Cells by Increasing Lactate and H3K18la Lactylation Levels
缺氧通过增加乳酸和H3K18la乳酸化水平促进水牛精原细胞的体外增殖
Mechanism of PAVA-induced toxicity and inflammation in a cocultured skin cell model
PAVA 在共培养皮肤细胞模型中诱发毒性和炎症的机制
Unravelling the mechanism by which vildagliptin and linagliptin inhibit pyroptosis in lung injury through the NLRP3 inflammatory pathway in type 1 diabetic rats.
揭示维格列汀和利格列汀通过 NLRP3 炎症通路抑制 1 型糖尿病大鼠肺损伤中细胞焦亡的机制
Harmine derivative H-2-168 induces the death of Echinococcus granulosus by regulating mitochondrial fusion and fission
哈尔明衍生物H-2-168通过调节线粒体融合和分裂诱导细粒棘球绦虫死亡
Activated TREM1-mediated MAPK signaling in endothelial cells caused by highly expressed STAT1 is associated with intracranial aneurysms occurrence and rupture.
STAT1 高表达引起的内皮细胞中 TREM1 介导的 MAPK 信号激活与颅内动脉瘤的发生和破裂有关
- 1
- 2
- 3
- 4
- 5
- 6
- 100