Anti-Alpha-synuclein antibody [4D6] - BSA and Azide free (Ab1903)

NACP, PARK1, SNCA, Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor

反应种属:Human
抗原名称:SNCA
应用:WB, IHC

详细信息

免疫原Recombinant Full Length Protein corresponding to Human SNCA. P37840
宿主/亚型Mouse / IgG1
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液Constituents: PBS
储存条件运输条件: Blue Ice 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白Yes

背景信息

What is this antibody validated in? Anti-Alpha-synuclein antibody [4D6] - BSA and Azide free (ab1903) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of Alpha-synuclein? Anti-Alpha-synuclein [4D6] - BSA and Azide free (ab1903) specifically detects a band for Alpha-synuclein (UniProt: P37840) at a molecular weight of 16kDa. Trusted by the scientific community Anti-Alpha-synuclein [4D6] - BSA and Azide free (ab1903) was first used in a scientific publication in 2004 and has been cited over 70 times in peer-reviewed journals. Reviewed by scientists Anti-Alpha-synuclein [4D6] - BSA and Azide free (ab1903) has over 5 independent reviews from customers.

文献引用 (75)

First-in-class SAM-competitive G9a inhibitor FLAV-27 as a disease-modifying therapy for Alzheimer disease.

首个SAM竞争性G9a抑制剂FLAV-27作为阿尔茨海默病疾病修饰疗法。

Bellver-Sanchis Aina, Valle-Garcia David, Barbaraci Carla, Romero-Becerra Fernando, Singh Rohit Kumar, Jarne-Ferrer Júlia, Vasilopoulou Foteini, Irisarri Alba, Martínez-Fernández Carmen, Fafián-Labora Juan A, Arufe María C, Wüst Carolin, Castellanos Aida, Soto David, Casals Núria, Fadó Rut, Pocock Jennifer M, Navarro Gemma, Val Cristina, Brea José, Loza M Isabel, Lleó Albert, Fortea Juan, Alcolea Daniel, Perez-Bosque Anna, Miró Lluïsa, Pérez Belén, Rashid Sajid, Ali Muhammad, Saqib Manahil, Lí Carbó Marcel, Guerrero Ana, Vázquez Santiago, Choudhary Bhanwar Singh, Dai Shaodong, Escolano Carmen, Franco Rafael, Pallàs Mercè, Griñán-Ferré Christian

Perivascular spread of CSF-derived α-synuclein oligomers drives region-specific Parkinson's-like pathology.

脑脊液衍生的α-突触核蛋白寡聚体在血管周围扩散,导致区域特异性的帕金森样病理。

Zhu Wen-Xin, He Xu-Zhong, Meng Jing-Cai, Dong Yi-Xuan, Hou Jing-Ru, Xue Rong, Zhang Guo-Xing, Wang Lin-Hui

Development of human targeted extracellular vesicles loaded with shRNA minicircles to prevent parkinsonian pathology.

开发载有 shRNA 微环的人类靶向细胞外囊泡,以预防帕金森氏症病理

Izco Maria, Sola Carlos, Schleef Martin, Schmeer Marco, de Toro María, Verona Guglielmo, Carlos Estefania, Reinares-Sebastian Alejandro, Colina Sandra, Marzo-Sola Maria Eugenia, Garcia-Sanmartin Josune, Fernández-Irigoyen Joaquín, Santamaría Enrique, Mugica-Vidal Rodolfo, Blesa Javier, Alvarez-Erviti Lydia

Lysophosphatidylcholine promoting α-Synuclein aggregation in Parkinson's disease: disrupting GCase glycosylation and lysosomal α-Synuclein degradation.

溶血磷脂酰胆碱促进帕金森病中α-突触核蛋白的聚集:破坏GCase糖基化和溶酶体α-突触核蛋白的降解

Mu Chunyan, Shao Kaiquan, Su Mingyu, Guo Yurong, Qiu Yuxiang, Sun Ruiao, Sun Sihan, Sun Yaoyu, Liu Chenkai, Wang Wei, Qin Xiaoling, Tang Chuanxi

Cannabidiol as a multifaceted therapeutic agent: mitigating Alzheimer's disease pathology and enhancing cognitive function.

大麻二酚作为一种多方面的治疗剂:减轻阿尔茨海默病病理并增强认知功能

Raïch Iu, Lillo Jaume, Rebassa Joan Biel, Griñán-Ferré Christian, Bellver-Sanchis Aina, Reyes-Resina Irene, Franco Rafael, Pallàs Mercè, Navarro Gemma

Regulation of mitochondrial dynamics and function by melatonin type 1 receptor in parkinson's disease.

褪黑素1型受体在帕金森病中对线粒体动力学和功能的调节。

Wang Xiao-Bo, Qi Li-Li, Wang Jian-Min, Sun Yan-Rui, Lv Qian-Kun, Cao Bing-Er, Jiang Shu-Min, Ma Quan-Hong, Liu Chun-Feng, Liu Jun-Yi, Wang Fen

Manganese exposure induces parkinsonism-like symptoms by Serpina3n-TFEB-v/p-ATPase signaling mediated lysosomal dysfunction

锰暴露通过 Serpina3n-TFEB-v/p-ATPase 信号介导的溶酶体功能障碍诱发帕金森病样症状

Huihui Hong, Sicheng Liu, Ting Yang, Jinxian Lin, Kun Luo, Yudong Xu, Ting Li, Yu Xi, Lingling Yang, Yuan-Qiang Lu, Wei Yuan, Zhou Zhou1

Competing chaperone pathways in α-synuclein disaggregation and aggregation dynamics.

α-突触核蛋白解聚和聚集动力学中的竞争性分子伴侣通路。

Auld Nicola K, McMahon Shannon, Marzano Nicholas R, van Oijen Antoine M, Ecroyd Heath

The Interplay Between CB(2) and NMDA Receptors in Parkinson's Disease.

CB(2)受体与NMDA受体在帕金森病中的相互作用。

Reyes-Resina Irene, Lillo Jaume, Raïch Iu, Rebassa Joan Biel, Capó Toni, Badia Pau, Navarro Gemma

PRNP E146G mutation inherited prion disease: distinctive clinical, pathological and fluid biomarker features.

PRNP E146G 突变遗传性朊病毒病:独特的临床、病理和体液生物标志物特征

Coysh Thomas, Jaunmuktane Zane, Hosszu Laszlo L P, Majbour Nour, Zhang Fuquan, Campbell Tracy, Darwent Lee, Matus Marcelo Barria, Chan Edgar, Holm-Mercer Leah, Mok Tze How, Wadsworth Jonathan D F, Bieschke Jan, Nithi Kannan, Brandner Sebastian, Smith Colin, Esiri Margaret, Collinge John, Mead Simon
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