Anti-PARP1 antibody [EPR18461] (Ab191217)
ADPRT, PPOL, PARP1, Poly [ADP-ribose] polymerase 1, PARP-1, ADP-ribosyltransferase diphtheria toxin-like 1, DNA ADP-ribosyltransferase PARP1, NAD(+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthase 1, Protein poly-ADP-ribosyltransferase PARP1, ARTD1, ADPRT 1
用户验证的应用
推荐稀释比例
- IHC-P1/1000 Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
- WB1/1000
- ICC/IF1/500
详细信息
背景信息
What is this antibody validated in? Anti-PARP1 antibody [EPR18461] (ab191217) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of PARP1? Anti-PARP1 [EPR18461] (ab191217) specifically detects a band for PARP1 (UniProt: P09874) at a molecular weight of 113kDa. Trusted by the scientific community Anti-PARP1 [EPR18461] (ab191217) was first used in a scientific publication in 2015 and has been cited over 80 times in peer-reviewed journals. Reviewed by scientists Anti-PARP1 [EPR18461] (ab191217) has over 5 independent reviews from customers. Specificity confirmed The specificity of Anti-PARP1 antibody [EPR18461] (ab191217) has been confirmed by Western blot testing in PARP1 Knockout HAP1 cell line, ab276094. Other related products We have a range of other formats of antibody clone [EPR18461] also available for your convenience: ab191217, Alexa Fluor® 488 - ab214954, Carrier free - ab222234, Alexa Fluor® 647 - ab311131, Alexa Fluor® 594 - ab311763, Alexa Fluor® 568 - ab313044, Alexa Fluor® 555 - ab313245, Alexa Fluor® 750 - ab321320 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies.
文献引用 (152)
Isoliensinine inhibits mitophagy and sensitizes T cell malignancies for STING-mediated NK clearance.
异莲心碱抑制线粒体自噬，使 T 细胞恶性肿瘤对 STING 介导的 NK 清除更加敏感。
Safe dosage and potential risks of chlorogenic acid: insights from in vitro and in vivo studies.
绿原酸的安全剂量和潜在风险：来自体外和体内研究的见解。
Bioengineered exosome-mRNA hybrids: a breakthrough in targeted miRNA delivery for diabetic kidney fibrosis therapy.
生物工程外泌体-mRNA杂交体：糖尿病肾纤维化治疗中靶向miRNA递送的突破。
PARP-1 couples β-catenin/TCF4 signaling to epithelial-mesenchymal transition in endometriosis.
PARP-1 将 β-catenin/TCF4 信号传导与子宫内膜异位症中的上皮-间质转化联系起来。
APOBEC3B enhances the efficacy of PARP inhibitors in elimination of ovarian cancer stem cell.
APOBEC3B 可增强 PARP 抑制剂清除卵巢癌干细胞的疗效。
CDK1âinduced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis.
CDK1 诱导的 p53 在 Ser315 位点的磷酸化调控介导了感染结核分枝杆菌临床分离株的巨噬细胞的细胞周期停滞和凋亡。
P53 Inhibition Diminishes IGSF9 Gene Activity to Promote DNA Repair and Exacerbate the Progression of Colon Cancer.
P53抑制会降低IGSF9基因活性，从而促进DNA修复并加剧结肠癌的进展。
Targeting ceramide metabolism to restore hypoxia-induced apoptosis in p53-deficient colon cancer cells.
通过靶向神经酰胺代谢来恢复 p53 缺陷型结肠癌细胞中缺氧诱导的细胞凋亡。
Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
在全身性缺氧和高海拔地区人群中，人类肿瘤的趋同遗传适应
Inhibition of RACGAP1 sensitizes triple-negative breast cancer cells to ferroptosis by regulating CPT1A-dependent fatty acid metabolism.
抑制 RACGAP1 可通过调节 CPT1A 依赖性脂肪酸代谢，使三阴性乳腺癌细胞对铁死亡更加敏感。
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