Nucleosomes have position-specific functions in controlling gene expression. A complete systematic genome-wide reference map of absolute and relative nucleosome positions is needed to minimize potential confusion when referring to the function of individual nucleosomes (or nucleosome-free regions) across datasets. We compiled six high-resolution genome-wide maps of Saccharomyces cerevisiae nucleosome positions from multiple labs and detection platforms, and report new insights. Data downloads, reference position assignment software, queries, and a visualization browser are available online http://atlas.bx.psu.edu/.
A compiled and systematic reference map of nucleosome positions across the Saccharomyces cerevisiae genome.
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作者:Jiang Cizhong, Pugh B Franklin
| 期刊: | Genome Biology | 影响因子: | 9.400 |
| 时间: | 2009 | 起止号: | 2009;10(10):R109 |
| doi: | 10.1186/gb-2009-10-10-r109 | ||
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