Embryonic stem cell-derived mesenchymal stem cells alleviate skeletal muscle injury induced by acute compartment syndrome
胚胎干细胞衍生的间充质干细胞减轻急性筋膜室综合征引起的骨骼肌损伤
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作者:Xiangkang Jiang #, Jingyuan Yang #, Fei Liu, Jiawei Tao, Jiefeng Xu, Mao Zhang
| 期刊: | Stem Cell Research | 影响因子: | 7.100 |
| 时间: | 2022 | 起止号: | 2022 Jul 15;13(1):313. |
| doi: | 10.1186/s13287-022-03000-0 | 方法学: | WB |
| 靶点: | MRC1 | 研究方向: | 发育与干细胞 |
| 细胞类型: | 干细胞 | |
Background
Acute compartment syndrome (ACS), a well-known complication of musculoskeletal injury,
Conclusion
Our findings suggest that embryonic stem cell-derived mesenchymal stem cells infusion could effectively alleviate ACS-induced skeletal muscle injury, in which the beneficial effects were related to the regulation of macrophages polarization.
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