Risk factors for deep venous thrombosis following total hip arthroplasty: a meta-analysis

全髋关节置换术后深静脉血栓形成的危险因素:一项荟萃分析

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Abstract

OBJECTIVE: We aim to investigate the predictors of deep venous thrombosis (DVT) following total hip arthroplasty (THA) by meta-analysis. METHODS: We collected potential indicators of DVT from related literature in the English databases of PubMed, Embase, and the Cochrane Library. We used RevMan 5.3 and STATA 12.0 to analyze potential indicators of DVT after THA. RESULTS: Finally, there were 6 English articles included in our study, and the rate of DVT after THA was 18.9% (270 of 1428 patients). Our findings indicated that advanced age [p<0.00001, OR = 4.51, 95% CI (2.91, 6.10)], female patients [p = 0.008, OR = 0.65, 95% CI (0.47, 0.89)], body mass index [p = 0.01, OR = 0.76, 95% CI (0.15, 1.37)], diabetes [p = 0.01, OR = 1.85, 95% CI (1.14, 3.01)], malignancy [p = 0.001, OR = 2.54, 95% CI (1.46, 4.41)], uncemented prosthesis[p = 0.0003, OR = 0.22, 95% CI (0.10, 0.50)], and longer operation time [p<0.00001, OR = 33.50, 95% CI (23.59, 43.41)] were predictors for DVT following THA. CONCLUSIONS: Many factors were found to be associated with DVT after THA. We provided references when we met the above characteristics of patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12959-025-00744-6.

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