Abstract
2-Propanol in the gaseous phase of clinical samples can serve as a biomarker for disease diagnosis. In this context, a novel fiber-optic Fabry-Perot (FP) interferometric sensor with a microtip structure was developed using the light-guided induced polymerization technique. The optical fiber sensor (OFS) with the best performance, measuring approximately 15 µm in length, exhibited good sensitivity to 2-propanol, with a response of -71.1 ± 2.1 pm/ppm. Additionally, it demonstrated good stability, with a maximum standard deviation of 0.15 nm and an estimated resolution of 3.18 ppm. The good sensitivity and ease of fabrication of this OFS highlight its potential for biomedical applications, particularly in non-invasive disease detection, given the role of 2-propanol as a biomarker for various health conditions.