Development of silicone-based phantoms for biomedical optics from 400 to 1550 nm

开发波长范围为 400 至 1550 nm 的硅基生物医学光学模型

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Abstract

This work describes the development of silicone-based evaluation phantoms for biomedical optics in the wavelength range from 400 to 1550 nm. The absorption coefficient μ (a) and the reduced scattering coefficient μs' were determined using an integrating sphere setup. Zirconium dioxide pigments were used as scatterers and carbon black as absorbers. We developed an in-house manufacturing process using a Hauschild SpeedMixer to ensure reproducibility. A set of nine cubic phantoms with three different reduced scattering and absorption coefficients was produced. Prediction of the μ (a) and μs' was done by using the weighted mass concentrations of the used materials. The average prediction accuracy over all wavelengths and phantoms is 1.0% for the reduced scattering coefficient and 3.5% for the absorption coefficient.

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