Bio-inspired cryo-ink preserves red blood cell phenotype and function during nanoliter vitrification

仿生冷冻墨水在纳升级玻璃化过程中保持红细胞表型和功能

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Abstract

Current red-blood-cell cryopreservation methods utilize bulk volumes, causing cryo-injury of cells, which results in irreversible disruption of cell morphology, mechanics, and function. An innovative approach to preserve human red-blood-cell morphology, mechanics, and function following vitrification in nanoliter volumes is developed using a novel cryo-ink integrated with a bioprinting approach.

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