Why is a dicationic digallene so reactive towards activation of strong covalent bonds? Scope and mechanistic investigations

为什么二阳离子二杂环戊烯对强共价键的活化反应如此迅速?反应范围和机理研究

阅读:2

Abstract

Herein, we investigate the reactivity of the trans-bent Ga⇄Ga double bond in the dicationic digallene [{Ga(dcpe)}(2)](2+) (dcpe = bis(dicyclohexylphosphino)ethane) as its [pf](-) salt ([pf](-) = [Al(OR(F))(4)](-); R(F) = C(CF(3))(3)), which is formed in situ within seconds. Unusually, this digallene is highly reactive towards covalent bonds and oxidatively adds even to strong E-Y σ-bonds, e.g., H-O, H-N, H-C and C-F bonds, under mild conditions, often at room temperature. Their bond activation at any cationic subvalent group 13 compound is unprecedented and the C-H bond activation is the first oxidative addition reported between any subvalent gallium compound and a neutral substrate. The scope and mechanism of the bond activation reactions were experimentally investigated by interaction with selected substrates and via isotope labelling experiments, as well as using high-level quantum chemical calculations. Mechanistically, the pronounced reactivity of the digallene can be attributed to an easily accessible asymmetric conformer with one (Lewis-acidic) planarized and one (Lewis-basic) pyramidalized reactive Ga-site, allowing for cooperative E-Y bond cleavage. In addition, the [2 + 2] cycloaddition of the Ga⇄Ga bond to C[double bond, length as m-dash]C double and triple bonds was studied: it follows a stepwise, non-concerted reaction mechanism, which allows for the catalytic isomerization of cis-olefins and may serve as the basis for follow-up functionalization reactions.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。