Change in type of sleep-disordered breathing from predominant central to obstructive sleep apnea following coronary artery bypass grafting

冠状动脉旁路移植术后,睡眠呼吸障碍类型由以中枢性为主转变为以阻塞性睡眠呼吸暂停为主

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Abstract

We report the case of a 67-year-old overweight man with reduced left ventricular ejection fraction (LVEF) due to myocardial infarction. He had an implantable cardioverter defibrillator (ICD) for frequent episodes of ventricular tachyarrhythmia and was initiated into adaptive-servo ventilation therapy for severe central sleep apnea (CSA), which was not suppressed by continuous positive airway pressure (CPAP). Since he still had several episodes of appropriate ICD therapies, coronary angiogram was performed, and severe three-vessel disease was found. He then underwent coronary artery bypass grafting (CABG). After CABG, his LVEF did not improve (from 29 to 25%); however, the B-type natriuretic peptide level decreased (from 560 to 330 pg/mL). Although the apnea-hypopnea index did not change (49.4 before and 55.1/h after CABG), his CSA converted to predominant obstructive sleep apnea accompanied by a shortening of the lung-to-finger circulation time (from 43 to 29 s) 2 weeks after CABG, which was completely suppressed by CPAP. .

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