What is already known about this topic?: Studies indicate that viruses could spread across species, but it is difficult to know when and where such small probability events occur because it is almost impossible to design an observational study on the whole landscape. What is added by this report?: We did a comprehensive analysis on the National Center for Biotechnology Information database and tried to find the time, place, and host that the viruses stayed in their long evolutionary history. What are the implications for public health practice?: Public databases are helpful to understand the risk of virus infection in humans and also a cost-effective method for monitoring public health and safety events.