Design of Paromomycin and Neomycin as Sulfated and Hydrophobic Glycans to Target Heparanase-Driven Tumor Progression and Metastasis.
将巴龙霉素和新霉素设计为硫酸化和疏水性聚糖,以靶向肝素酶驱动的肿瘤进展和转移
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00937
Abdulsalam Hawau, Philip Livia, Singh Kartikey, Farhoud Malik, Ilan Neta, Vlodavsky Israel, Nguyen Hien M