日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The PI3K pathway is a downstream effector of NRF2 activation in the esophagus

PI3K通路是食管中NRF2激活的下游效应因子。

Subramaniyan, Boopathi; Li, Yahui; Xiong, Zhaohui; Paiboonrungruang, Chorlada; Bui-Linh, Candice; Spitz, Francis; Chen, Xiaoxin

Lymphatic Metastasis of Esophageal Squamous Cell Carcinoma: The Role of NRF2 and Therapeutic Strategies

食管鳞状细胞癌淋巴转移:NRF2 的作用及治疗策略

Li, Yahui; Ladd, Zachary; Xiong, Zhaohui; Bui-Linh, Candice; Paiboonrungruang, Chorlada; Subramaniyan, Boopathi; Li, Huan; Wang, Haining; Balch, Curt; Shersher, David D; Spitz, Francis; Chen, Xiaoxin

Pyrimethamine and a potent analog inhibit NRF2 by suppressing one-carbon metabolism.

乙胺嘧啶及其强效类似物通过抑制一碳代谢来抑制 NRF2。

Chembo Julius, Bowman Brittany M, Lapak Kyle, Wilkerson Emily, Wamsley Nathan T, Paiboonrungruang Chorlada, Cho Kevin, Medcalf Matthew R, Wang Haining, Patti Gary J, Dolle Roland E, Chen Xiaoxin, Zolkind Paul, Major Michael B

Pyrimethamine and a potent analogue WCDD115 inhibit NRF2 by suppressing DHFR and one-carbon metabolism

乙胺嘧啶及其强效类似物 WCDD115 通过抑制 DHFR 和一碳代谢来抑制 NRF2

Julius Chembo, Brittany M Bowman, Kyle Lapak, Emily Wilkerson, Chorlada Paiboonrungruang, Kevin Cho, Matthew R Medcalf, Gary J Patti, Roland E Dolle, Xiaoxin Chen, Paul Zolkind, Michael B Major

Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia

小分子筛选鉴定出乙胺嘧啶是 NRF2 驱动的食管增生的抑制剂

Chorlada Paiboonrungruang, Zhaohui Xiong, David Lamson, Yahui Li, Brittany Bowman, Julius Chembo, Caizhi Huang, Jianying Li, Eric W Livingston, Jon E Frank, Vivian Chen, Yong Li, Bernard Weissman, Hong Yuan, Kevin P Williams, M Ben Major, Xiaoxin Chen

Lymphatic Drainage System and Lymphatic Metastasis of Cancer Cells in the Mouse Esophagus

小鼠食管淋巴引流系统与癌细胞淋巴转移

Yahui Li, Qing Cheng, Zhaohui Xiong, Chorlada Paiboonrungruang, Timothy Adekoya, Yong Li, Xiaoxin Chen

PAX9 in Cancer Development

PAX9 在癌症发展中的作用

Chen, Xiaoxin; Li, Yahui; Paiboonrungruang, Chorlada; Li, Yong; Peters, Heiko; Kist, Ralf; Xiong, Zhaohui

Development of targeted therapy of NRF2(high) esophageal squamous cell carcinoma

针对NRF2(高表达)食管鳞状细胞癌的靶向治疗研究

Paiboonrungruang, Chorlada; Simpson, Emily; Xiong, Zhaohui; Huang, Caizhi; Li, Jianying; Li, Yahui; Chen, Xiaoxin

NRF2/ACSS2 axis mediates the metabolic effect of alcohol drinking on esophageal squamous cell carcinoma

NRF2/ACSS2轴介导饮酒对食管鳞状细胞癌的代谢影响

Joab Otieno Odera, Zhaohui Xiong, Caizhi Huang, Ning Gu, Wenjun Yang, Jessie Githang'a, Elizabeth Odera, Chorlada Paiboonrungruang, Xiaoxin Chen

Targeted therapy of esophageal squamous cell carcinoma: the NRF2 signaling pathway as target

食管鳞状细胞癌的靶向治疗:以NRF2信号通路为靶点

Ma, Shaohua; Paiboonrungruan, Chorlada; Yan, Tiansheng; Williams, Kevin P; Major, M Ben; Chen, Xiaoxin Luke