日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural and Functional Impacts of SARS-CoV-2 Spike Protein Mutations: Insights From Predictive Modeling and Analytics

SARS-CoV-2刺突蛋白突变的结构和功能影响:来自预测建模和分析的启示

Netsey, Edem K; Naandam, Samuel M; Asante Jnr, Joseph; Abraham, Kuukua E; Yadem, Aayire C; Owusu, Gabriel; Shaffer, Jeffrey G; Srivastav, Sudesh K; Doumbia, Seydou; Owusu-Dabo, Ellis; Morkle, Chris E; Yemeh, Desmond; Manortey, Stephen; Yankson, Ernest; Sangare, Mamadou; Kakraba, Samuel

Correction: Structural and Functional Impacts of SARS-CoV-2 Spike Protein Mutations: Insights From Predictive Modeling and Analytics

更正:SARS-CoV-2 刺突蛋白突变的结构和功能影响:来自预测建模和分析的见解

Netsey, Edem K; Naandam, Samuel M; Asante Jnr, Joseph; Abraham, Kuukua E; Yadem, Aayire C; Owusu, Gabriel; Shaffer, Jeffrey G; Srivastav, Sudesh K; Doumbia, Seydou; Owusu-Dabo, Ellis; Morkle, Chris E; Yemeh, Desmond; Manortey, Stephen; Yankson, Ernest; Sangare, Mamadou; Kakraba, Samuel

Enantiomeric Separation, Absolute Configuration by X-ray Crystallographic Analysis, and Functional Evaluation of Enantiomers of the Dual Ligand, SYA0340 at 5-HT1A and 5-HT7A Receptors

对映体分离、X 射线晶体学分析绝对构型以及双配体 SYA0340 对 5-HT1A 和 5-HT7A 受体的功能评估

Barbara A Bricker, Chandrashekhar Voshavar, Edem K Onyameh, Uma M Gonela, Xinsong Lin, Tracy L Swanson, Laura B Kozell, Jennifer L Schmachtenberg, Shelley H Bloom, Aaron J Janowsky, Seth Y Ablordeppey

De novo mutation rates at the single-mutation resolution in a human HBB gene region associated with adaptation and genetic disease

与适应和遗传疾病相关的人类 HBB 基因区域中单突变分辨率的从头突变率

Daniel Melamed, Yuval Nov, Assaf Malik, Michael B Yakass, Evgeni Bolotin, Revital Shemer, Edem K Hiadzi, Karl L Skorecki, Adi Livnat

Design and discovery of a high affinity, selective and β-arrestin biased 5-HT7 Receptor Agonist

设计和发现高亲和力、选择性和 β-arrestin 偏向的 5-HT7 受体激动剂

Edem K Onyameh, Edward Ofori, Barbara A Bricker, Uma M Gonela, Suresh V K Eyunni, Hye J Kang, Chandrashekar Voshavar, Seth Y Ablordeppey

Determinants of COVID-19 vaccine acceptance and hesitancy among healthcare professionals in the Kintampo North Municipality, Bono East Region, Ghana

加纳博诺东部地区金坦波北部市医护人员对新冠疫苗接受度和犹豫程度的决定因素

Asumah, Mubarick N; Abubakari, Abdulai; Fosu, Brian; Dzantor, Edem K; Agyapong, Prince D; Harrison, Samuel Be; Apio, Gavin; Abukari, Abdul-Kahar

New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263

源自 SYA16263 的新型双 5-HT1A 和 5-HT7 受体配体

Edward Ofori, Edem K Onyameh, Uma M Gonela, Chandrashekhar Voshavar, Barbara Bricker, Tracy L Swanson, Amy J Eshleman, Jennifer L Schmachtenberg, Shelley H Bloom, Aaron J Janowsky, Seth Y Ablordeppey

A study of the structure-affinity relationship in SYA16263; is a D2 receptor interaction essential for inhibition of apormorphine-induced climbing behavior in mice?

SYA16263 的结构亲和力关系研究;D2 受体相互作用对于抑制阿扑吗啡诱导的小鼠攀爬行为是否至关重要?

Edem K Onyameh, Barbara A Bricker, Suresh V K Eyunni, Chandrashekhar Voshavar, Uma M Gonela, Edward Ofori, Andrea Jenkins, Seth Y Ablordeppey

Enantioseparation of 5-chloro-2-{2-[3,4-dihydroisoquinoline-2(1H)-yl]ethyl}-2-methyl-2,3-dihydro-1H-inden-1-one (SYA 40247), a high-affinity 5-HT7 receptor ligand, by HPLC-PDA using amylose tris-(3, 5- dimethylphenylcarbamate) as a chiral stationary phase

使用直链淀粉三-(3, 5-二甲基苯基氨基甲酸酯)作为手性固定相,通过 HPLC-PDA 对 5-氯-2-{2-[3,4-二氢异喹啉-2(1H)-基]乙基}-2-甲基-2,3-二氢-1H-茚-1-酮 (SYA 40247)(一种高亲和力的 5-HT7 受体配体)进行对映体分离

Edem K Onyameh, Barbara A Bricker, Edward Ofori, Seth Y Ablordeppey

Development of CNS multi-receptor ligands: Modification of known D2 pharmacophores

中枢神经系统多受体配体的开发:已知 D2 药效团的修饰

Jagan R Etukala, Xue Y Zhu, Suresh V K Eyunni, Edem K Onyameh, Edward Ofori, Barbara A Bricker, Hye J Kang, Xi-Ping Huang, Bryan L Roth, Seth Y Ablordeppey