日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deaths with preceding hospitalisations within 180 days in eight countries in sub-Saharan Africa and South Asia: A secondary descriptive analysis of the Child Health and Mortality Prevention Surveillance (CHAMPS) network

撒哈拉以南非洲和南亚八个国家中,死亡前180天内曾住院的病例:儿童健康和死亡预防监测(CHAMPS)网络的二次描述性分析

Varo, Rosauro; Cole, Kaitlin; Madewell, Zachary J; Iglesias, Jaime Fanjul; Igunza, Kitiezo Aggrey; Akelo, Victor; Mugah, Christopher; Onyango, Dickens; Were, Joyce A; Madhi, Shabir A; Dangor, Ziyaad; Johnstone, Siobhan; Lala, Sanjay G; Ruder, Tanya; Mandomando, Inacio; Kincardett, Milton; Xerinda, Elisio G; Scott, J Anthony G; Assefa, Nega; Madrid, Lola; Hassen, Faisel A; Edris, Yunus; Ogbuanu, Ikechukwu; Bassey, Ima-Abasi; Samura, Solomon; Sillah, Abdul Salaam; Kaluma, Erick; Arifeen, Shams El; Biswas, Rajib; Gurley, Emily S; Rahman, Afruna; Hossain, Mohammad Zahid; Omer, Saad B; Kazi, Abdul Momin; Belgaumi, Sameer M; Allana, Raheel; Keita, Adama M; Bassat, Quique; Mutevedzi, Portia C; Whitney, Cynthia G; Rees, Chris A

Activating Ras-MAPK pathway variants drive hippocampal clonal competition in human epilepsy

激活Ras-MAPK通路变体驱动人类癫痫海马克隆竞争

Khoshkhoo, Sattar; Bae, Mingyun; Wang, Yilan; Tillett, Ashton; Ramirez, Rosita B; Finander, Benjamin; Egan, Emily D; Marx, Linus; Patel, Dipan; Zhou, Zinan; Chahine, Yasmine; Chhouk, Brian; Zoullas, Sofia M; Lai, Abbe; Coras, Roland; Bielle, Franck; Navarro, Vincent; Mathon, Bertrand; Valiante, Taufik A; Moradi Chameh, Homeira; Gao, Andrew F; Krings, Timo; Gooley, Samuel; Hildebrand, Michael S; Bulluss, Kristian; Clark, Jonathan; Morokoff, Andrew P; King, James A; Todaro, Marian; Kwan, Patrick; O'Brien, Terence J; Berkovic, Samuel F; Scheffer, Ingrid E; Perucca, Piero; Lapinskas, Emily; Rolston, John D; Cosgrove, G Rees; Sarkis, Rani A; D'Gama, Alissa M; Alexadrescu, Sanda; Yang, Edward; Poduri, Annapurna; Richardson, R Mark; Erson-Omay, E Zeynep; DeLanerolle, Nihal; Spencer, Dennis D; Brown, Katherine S-M; Miller, Michael B; Roberts, Amy E; Santos, Luana N; Kontaridis, Maria I; Bien, Christian G; Blacklow, Stephen C; Kahle, Kristopher T; Blümcke, Ingmar; Huang, August Yue; Lee, Eunjung Alice; Walsh, Christopher A

Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer

通过p300/CBP降解靶向组蛋白H2B乙酰化增强子在前列腺癌中的应用

Jie Luo # ,Zhixiang Chen # ,Yuanyuan Qiao # ,Jean Ching-Yi Tien ,Eleanor Young ,Rahul Mannan ,Somnath Mahapatra ,Rupam Bhattacharyya ,Lanbo Xiao ,Tongchen He ,Sanjana Eyunni ,Yuping Zhang ,Yang Zheng ,Fengyun Su ,Xuhong Cao ,Rui Wang ,Yunhui Cheng ,Rithvik Seri ,James George ,Miriam Shahine ,Stephanie J Miner ,Matthew G Rees ,Melissa M Ronan ,Jennifer A Roth ,Ulka Vaishampayan ,Mi Wang ,Shaomeng Wang ,Abhijit Parolia ,Arul M Chinnaiyan

Defining the Antitumor Mechanism of Action of a Clinical-stage Compound as a Selective Degrader of the Nuclear Pore Complex

将临床阶段化合物的抗肿瘤作用机制定义为核孔复合物的选择性降解剂。

Linjie Yuan,Wenzhi Ji,Brendan G Dwyer,Joey Lu,Jing Bian,Gianna M Colombo,Michael J Martinez,Daniel Fernandez,Nick A Phillips,Michelle T Tang,Christine Wenjie Zhou,Nirk E Quispe Calla,Cesar Guzman Huancas,Michael Eckart,Jessica Tran,Hannah M Jones,Tian Qiu,John G Doench,Matthew G Rees,Jennifer A Roth,Michael D Cameron,Gregory W Charville,Calvin J Kuo,Scott J Dixon,Tinghu Zhang,Stephen M Hinshaw,Nathanael S Gray,Steven M Corsello

AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients with MTAP-Deleted Cancers

AMG 193 是一种临床阶段 MTA 协同 PRMT5 抑制剂,可在临床前和 MTAP 缺失癌症患者中发挥抗肿瘤活性

Brian Belmontes #, Katherine K Slemmons #, Chun Su, Siyuan Liu, Antonia N Policheni, Jodi Moriguchi, Hong Tan, Fang Xie, Daniel Andrew Aiello, Yajing Yang, Raul Lazaro, Famke Aeffner, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Mikkel Vestergaard, Sanne Cowland, Jan Andersson, Ian Sarvary, Qin

Adherence to Perinatal Asphyxia or Sepsis Management Guidelines in Low- and Middle-Income Countries

低收入和中等收入国家对围产期窒息或败血症管理指南的遵循情况

Rahman, Afruna; Ray, Meghna; Madewell, Zachary J; Igunza, Kitiezo Aggrey; Akelo, Victor; Onyango, Dickens; Murila, Florence; Mwebia, Winnie; Ogbuanu, Ikechukwu Udo; Ojulong, Julius; Kowuor, Dickens; Kaluma, Erick; Samura, Solomon; El Arifeen, Shams; Gurley, Emily S; Hossain, Mohammad Zahid; Islam, Kazi Munisul; Biswas, Rajib; Assefa, Nega; Teferi, Temesgen; Eshetu, Konjit; Madrid, Lola; Kotloff, Karen L; Tapia, Milagritos D; Keita, Adama Mamby; Xerinda, Elisio; de Assis, Celisa Mendonça; Kincardett, Milton; Mandomado, Inacio; Varo, Rosauro; Madhi, Shabir A; Dangor, Ziyaad; Baba, Vuyelwa; Velaphi, Sithembiso; Adam, Yasmin; Blau, Dianna M; Mutevedzi, Portia C; Bassat, Quique; Whitney, Cynthia G; Rees, Chris A

Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification

泛KRAS抑制剂BI-2493和BI-2865在KRAS野生型等位基因扩增的肿瘤中显示出强大的抗肿瘤活性

Antonio Tedeschi # ,Fiorella Schischlik # ,Francesca Rocchetti # ,Johannes Popow ,Florian Ebner ,Daniel Gerlach ,Antonia Geyer ,Valeria Santoro ,Andrew S Boghossian ,Matthew G Rees ,Melissa M Ronan ,Jennifer A Roth ,Jesse Lipp ,Matthias Samwer ,Michael Gmachl ,Norbert Kraut ,Mark Pearson ,Dorothea Rudolph

Unilateral magnetic resonance-guided focused ultrasound for medication-refractory essential tremor: 5-year continued access study

单侧磁共振引导聚焦超声治疗药物难治性特发性震颤:5年持续入组研究

Ghanouni, Pejman; Krishna, Vibhor; Eisenberg, Howard M; Elias, W Jeffrey; Cosgrove, G Rees; Gwinn, Ryder; Kaplitt, Michael G; Baltuch, Gordon H

New technique for direct targeting of the ventral intermediate nucleus using magnetic resonance-guided focused ultrasound

利用磁共振引导聚焦超声直接靶向腹侧中间核的新技术

Aibar-Duran, Juan Ángel; Akira Watanabe, Rodrigo; McDannold, Nathan J; Cosgrove, G Rees

Validation of a novel simulated tendon model for core suture tendon repair

验证一种用于肌腱核心缝合修复的新型模拟肌腱模型

Western, L; Roberts, P G; Rees, J; Howgate, D