日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Paradoxical SERCA2a Dysregulation Contributes to Atrial Fibrillation in a Model of Diet-Induced Obesity.

SERCA2a 矛盾性失调导致饮食诱导肥胖模型中出现心房颤动

Ponce-Balbuena Daniela, Tyrrell Daniel J, Cruz-Cortés Carlos, Guerrero-Serna Guadalupe, Monteiro Da Rocha Andre, Herron Todd J, Song Jianrui, Raza Danyal S, Anumonwo Justus, Goldstein Daniel R, Espinoza-Fonseca L Michel

Replacement of Lys27 by asparagine in the SERCA regulator myoregulin: A Ca(2+) affinity modulator or a catalytic activity switch?

SERCA调节蛋白肌调节蛋白中Lys27被天冬酰胺取代:是Ca(2+)亲和力调节剂还是催化活性开关?

Rathod, Nishadh; Guerrero-Serna, Guadalupe; Young, Howard S; Espinoza-Fonseca, L Michel

Paradoxical SERCA dysregulation contributes to atrial fibrillation in a model of diet-induced obesity

SERCA 失调导致饮食诱发肥胖模型中的心房颤动

Daniela Ponce-Balbuena, Daniel J Tyrrell, Carlos Cruz-Cortés, Guadalupe Guerrero-Serna, Andre Monteiro Da Rocha, Todd J Herron, Jianrui Song, Danyal S Raza, Justus Anumonwo, Daniel R Goldstein, L Michel Espinoza-Fonseca

A novel machine learning-based screening identifies statins as inhibitors of the calcium pump SERCA

一种基于机器学习的新型筛选方法将他汀类药物鉴定为钙泵 SERCA 的抑制剂

Carlos Cruz-Cortés, M Andrés Velasco-Saavedra, Eli Fernández-de Gortari, Guadalupe Guerrero-Serna, Rodrigo Aguayo-Ortiz, L Michel Espinoza-Fonseca

Mechanisms for cardiac calcium pump activation by its substrate and a synthetic allosteric modulator using fluorescence lifetime imaging

使用荧光寿命成像研究心脏钙泵由其底物和合成变构调节剂激活的机制

Jaroslava Šeflová, Carlos Cruz-Cortés, Guadalupe Guerrero-Serna, Seth L Robia, L Michel Espinoza-Fonseca

SNTA1 gene rescues ion channel function and is antiarrhythmic in cardiomyocytes derived from induced pluripotent stem cells from muscular dystrophy patients

SNTA1 基因可挽救肌营养不良症患者诱导性多能干细胞衍生的心肌细胞的离子通道功能并具有抗心律失常作用

Eric N Jimenez-Vazquez, Michael Arad, Álvaro Macías, Maria L Vera-Pedrosa, Francisco Miguel Cruz, Lilian K Gutierrez, Ashley J Cuttitta, André Monteiro da Rocha, Todd J Herron, Daniela Ponce-Balbuena, Guadalupe Guerrero-Serna, Ofer Binah, Daniel E Michele, José Jalife

Transcriptome and proteome mapping in the sheep atria reveal molecular featurets of atrial fibrillation progression

绵羊心房转录组和蛋白质组图谱揭示了心房颤动进展的分子特征

Alvarez-Franco, Alba; Rouco, Raquel; Ramirez, Rafael J; Guerrero-Serna, Guadalupe; Tiana, Maria; Cogliati, Sara; Kaur, Kuljeet; Saeed, Mohammed; Magni, Ricardo; Enriquez, Jose Antonio; Sanchez-Cabo, Fatima; Jalife, José; Manzanares, Miguel

Human influenza A virus causes myocardial and cardiac-specific conduction system infections associated with early inflammation and premature death

人类甲型流感病毒引起心肌和心脏特异性传导系统感染,与早期炎症和过早死亡有关

David Filgueiras-Rama, Jasmina Vasilijevic, Jose Jalife, Sami F Noujaim, Jose M Alfonso, Jose A Nicolas-Avila, Celia Gutierrez, Noelia Zamarreño, Andres Hidalgo, Alejandro Bernabé, Christopher Pablo Cop, Daniela Ponce-Balbuena, Guadalupe Guerrero-Serna, Daniel Calle, Manuel Desco, Jesus Ruiz-Cabello

A multiscale approach for bridging the gap between potency, efficacy, and safety of small molecules directed at membrane proteins

一种多尺度方法,用于弥合针对膜蛋白的小分子的效力、功效和安全性之间的差距

Rodrigo Aguayo-Ortiz #, Jeffery Creech #, Eric N Jiménez-Vázquez, Guadalupe Guerrero-Serna, Nulang Wang, Andre Monteiro da Rocha, Todd J Herron, L Michel Espinoza-Fonseca

Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents

Kir2.1 相互作用组图揭示 PKP4 是 Kir2.1 调节的内向整流钾电流的调节剂

Sung-Soo Park, Daniela Ponce-Balbuena, Rork Kuick, Guadalupe Guerrero-Serna, Justin Yoon, Dattatreya Mellacheruvu, Kevin P Conlon, Venkatesha Basrur, Alexey I Nesvizhskii, José Jalife, Jean-François Rual