日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy

核膜恶化导致的核周损伤会引发应激反应,从而导致 LMNA 心肌病

Kunal Sikder, Elizabeth Phillips, Zhijiu Zhong, Nadan Wang, Jasmine Saunders, David Mothy, Andrew Kossenkov, Timothy Schneider, Zuzana Nichtova, Gyorgy Csordas, Kenneth B Margulies, Jason C Choi

Med25 Limits Master Regulators That Govern Adipogenesis

Med25 限制控制脂肪生成的主调节因子

Jasmine Saunders, Kunal Sikder, Elizabeth Phillips, Anurag Ishwar, David Mothy, Kenneth B Margulies, Jason C Choi

Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival

层蛋白 A/C 基因突变引起的心肌病中双特异性蛋白磷酸酶 4 升高主要依赖于 ERK1/2,其消耗可改善心脏功能和生存率

Jason C Choi, Wei Wu, Elizabeth Phillips, Robin Plevin, Fusako Sera, Shunichi Homma, Howard J Worman

Inhibition of extracellular signal-regulated kinase 1/2 signaling has beneficial effects on skeletal muscle in a mouse model of Emery-Dreifuss muscular dystrophy caused by lamin A/C gene mutation

抑制细胞外信号调节激酶 1/2 信号传导对由层蛋白 A/C 基因突变引起的 Emery-Dreifuss 肌营养不良症小鼠模型中的骨骼肌具有有益影响

Antoine Muchir, Young Jin Kim, Sarah A Reilly, Wei Wu, Jason C Choi, Howard J Worman

Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation

替西罗莫司激活自噬并改善层蛋白A/C基因突变引起的心肌病

Jason C Choi, Antoine Muchir, Wei Wu, Shinichi Iwata, Shunichi Homma, John P Morrow, Howard J Worman

Dual specificity phosphatase 4 mediates cardiomyopathy caused by lamin A/C (LMNA) gene mutation

双特异性磷酸酶 4 介导层蛋白 A/C (LMNA) 基因突变引起的心肌病

Jason C Choi, Wei Wu, Antoine Muchir, Shinichi Iwata, Shunichi Homma, Howard J Worman

Blocking farnesylation of the prelamin A variant in Hutchinson-Gilford progeria syndrome alters the distribution of A-type lamins

阻断哈钦森-吉尔福德早衰综合征中前层蛋白 A 变体的法呢基化会改变 A 型层蛋白的分布

Yuexia Wang, Cecilia Ostlund, Jason C Choi, Theresa C Swayne, Gregg G Gundersen, Howard J Worman

Histone deacetylases inhibit IFN-gamma-inducible gene expression in mouse trophoblast cells

组蛋白去乙酰化酶抑制小鼠滋养层细胞中 IFN-γ 诱导基因的表达

Jason C Choi, Renae Holtz, Shawn P Murphy

Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins

核骨架和细胞骨架 (LINC) 复合蛋白的动力学和分子相互作用

Cecilia Ostlund, Eric S Folker, Jason C Choi, Edgar R Gomes, Gregg G Gundersen, Howard J Worman