日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Therapeutic Potential of 1‑(1,2,3,5,6,7-Hexahydro‑s‑indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea (MCC950), a Potent Agent for Improving Autoinflammatory Hearing Loss in Mice with Myeloid Cell-Specific Conditional Expression of Mutant Nucleotide-Binding Oligomerization Domain, Leucine-Rich Repeat, and Pyrin Domain-Containing Protein 3 (Nlrp3)

1‑(1,2,3,5,6,7-六氢‑s‑茚满-4-基)-3-[4-(2-羟基丙烷-2-基)呋喃-2-基]磺酰脲 (MCC950) 的治疗潜力,一种改善髓系细胞特异性条件表达突变核苷酸结合寡聚化结构域、富含亮氨酸重复序列和吡啶结构域蛋白 3 (Nlrp3) 的小鼠自身炎症性听力损失的有效药物

Tran, Ngoc-Trinh; Kim, Bong Jik; Kim, Minyoung; Jang, Pil Geum; Jinhee, Han; Yang, Jiyeon; Kim, Ju Ang; Park, Joo-Young; Paik, Jin Ho; Kim, Yehree; Choi, Byung Yoon

Electrophysiological and histological study reveals hidden subclinical haploinsufficiency of Otof

电生理和组织学研究揭示了Otof基因隐匿的亚临床单倍体功能不全

Han, Kyu-Hee; Kim, Yehree; Kang, Kwon Woo; Kim, Ju Ang; Oh, Yonghee; Kim, Min Young; Han, Jin Hee; Kim, Bong Jik; Yi, Eunyoung; Choi, Byung Yoon

The guanine nucleotide exchange factor DOCK5 negatively regulates osteoblast differentiation and BMP2-induced bone regeneration via the MKK3/6 and p38 signaling pathways

鸟嘌呤核苷酸交换因子 DOCK5 通过 MKK3/6 和 p38 信号通路负向调节成骨细胞分化和 BMP2 诱导的骨再生

Ju Ang Kim, Soomin Im, Jiwon Lim, Jung Min Hong, Hye Jung Ihn, Jong-Sup Bae, Jung-Eun Kim, Yong Chul Bae, Eui Kyun Park

Microvilli control the morphogenesis of the tectorial membrane extracellular matrix.

微绒毛控制着盖膜细胞外基质的形态发生

Niazi Ava, Kim Ju Ang, Kim Dong-Kyu, Lu Di, Sterin Igal, Park Joosang, Park Sungjin

A novel BCAP31 variant associated with nonsyndromic auditory neuropathy spectrum disorder: mitochondrial dysfunction, cisplatin sensitivity, and amenability to mitochondrial transplantation

一种与非综合征性听觉神经病谱系障碍相关的新型BCAP31变异:线粒体功能障碍、顺铂敏感性和线粒体移植适应性

Kim, Yehree; Kim, Yujin; Kim, Bong Jik; Yu, Shin-Hye; Han, Jin Hee; Kim, Minyoung; Yi, Nayoung; Lee, Seo-Eun; Kim, Ju Ang; Han, Kyuboem; Kim, Chun-Hyung; Kang, Young Cheol; Choi, Byung Yoon

Impact of HOMER2 frameshift extension variant on auditory function and development.

HOMER2移码扩展变异对听觉功能和发育的影响

Han Eunjung, Kim Ju Ang, Park Saemi, Han Jin Hee, Kim Min Young, Kim Yehree, Tran Ngoc-Trinh, Kim Bong Jik, Choi June, Choi Byung Yoon

In vivo consequences of varying degrees of OTOA alteration elucidated using knock-in mouse models and pseudogene contamination-free long-read sequencing

利用基因敲入小鼠模型和无假基因污染的长读长测序技术,阐明了不同程度的OTOA改变在体内的影响。

Kim, Ju Ang; Kim, Bong Jik; Lee, Chung; Seo, Go Hun; Lee, Hane; Han, Jin Hee; Niazi, Ava; Park, Joosang; Choi, Byung Yoon; Park, Sungjin

Otof gene transfer in DFNB9 mice carrying human founder non-truncating alleles

在携带人类创始人非截断等位基因的DFNB9小鼠中进行Otof基因转移

Kim, Yehree; Chung, Yoojin; Kim, Ju Ang; Han, Kyu Hee; Kang, Kwon Woo; Tran, Ngoc-Trinh; Kim, Min Young; Yi, Eunyoung; Jung, Sangyong; Kim, Bong Jik; Artinian, Quynh-Anh; Koehler, Seth D; Pan, Ning; Gibson, Tyler M; Becker, Lars; Goodliffe, Joseph W; Kalker, Molly; Barnes, Madeline; Shaheen, Luke A; Drummond, Meghan C; Valayannopoulos, Vassili; Choi, Byung Yoon

The transcription factor BBX regulates phosphate homeostasis through the modulation of FGF23

转录因子 BBX 通过调节 FGF23 来调节磷酸盐稳态

Su Jeong Lee, Ju Ang Kim, Hye Jung Ihn, Je-Yong Choi, Tae-Yub Kwon, Hong-In Shin, Eui-Sic Cho, Yong Chul Bae, Rulang Jiang, Jung-Eun Kim, Eui Kyun Park

Glycinamide Facilitates Nanocomplex Formation and Functions Synergistically with Bone Morphogenetic Protein 2 to Promote Osteoblast Differentiation In Vitro and Bone Regeneration in a Mouse Calvarial Defect Model.

甘氨酰胺促进纳米复合物的形成,并与骨形态发生蛋白 2 协同作用,在体外促进成骨细胞分化,并在小鼠颅骨缺损模型中促进骨再生

Nam Sang-Hyeon, Kim Ju Ang, Lim Soomin, Lee Su Jeong, Kim Chun-Ho, Bae Jong-Sup, Boo Yong Chool, Kim Young-Jin, Park Eui Kyun