Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity.
定向破坏 IL2 聚集和受体结合位点,可产生具有更高特异性和更强生产能力的定制生物制剂
期刊:Computational and Structural Biotechnology Journal
影响因子:4.1
doi:10.1016/j.csbj.2025.03.002
Dashwood Amy, Makuyana Ntombizodwa, van der Kant Rob, Ghodsinia Arman, Hernandez Alvaro R, Lienart Stephanie, Burton Oliver, Dooley James, Ali Magda, Kouser Lubna, Naranjo Francisco, Holt Matthew G, Rousseau Frederic, Schymkowitz Joost, Liston Adrian