日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

脑脊液中前脑啡肽水平可预测亨廷顿病患者纹状体萎缩,且早于临床运动症状的诊断数十年。

Farag, Mena; Murphy, Michael J; Hobbs, Nicola Z; Leocadi, Michela; Fayer, Kate; Thackeray, Olivia; Gobom, Johan; Ciosi, Marc; Heslegrave, Amanda; Zetterberg, Henrik; Langbehn, Douglas R; Monckton, Darren G; Wild, Edward J; Tabrizi, Sarah J; Scahill, Rachael I

Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington's disease decades before clinical motor diagnosis

亨廷顿病患者血液中体细胞CAG重复序列扩增与神经退行性变生物标志物相关,且这种关联在临床运动症状出现前数十年就已存在。

Scahill, Rachael I; Farag, Mena; Murphy, Michael J; Hobbs, Nicola Z; Leocadi, Michela; Langley, Christelle; Knights, Harry; Ciosi, Marc; Fayer, Kate; Nakajima, Mitsuko; Thackeray, Olivia; Gobom, Johan; Rönnholm, John; Weiner, Sophia; Hassan, Yara R; Ponraj, Nehaa K P; Estevez-Fraga, Carlos; Parker, Christopher S; Malone, Ian B; Hyare, Harpreet; Long, Jeffrey D; Heslegrave, Amanda; Sampaio, Cristina; Zhang, Hui; Robbins, Trevor W; Zetterberg, Henrik; Wild, Edward J; Rees, Geraint; Rowe, James B; Sahakian, Barbara J; Monckton, Darren G; Langbehn, Douglas R; Tabrizi, Sarah J

Challenges and advances for huntingtin detection in cerebrospinal fluid: in support of relative quantification.

脑脊液中亨廷顿蛋白检测的挑战与进展:支持相对定量

Harding Rachel J, Xie Yuanyun, Caron Nicholas S, Findlay-Black Hailey, Lyu Caroline, Potluri Nalini, Chandrasekaran Renu, Hayden Michael R, Leavitt Blair R, Langbehn Douglas R, Southwell Amber L

Age-Dependent Effects of Loss of Contactin-Associated Protein-Like 2, an Autism-Associated Gene, on the Acquisition and Recall of Fear Memory

自闭症相关基因——接触蛋白相关蛋白样2(Contactin-Associated Protein-Like 2)缺失对恐惧记忆的习得和回忆的年龄依赖性影响

Taugher-Hebl, R J; Berns, A; Jones, M; Townsend, A; Eagen, A K; Ferri, Sarah L; Langbehn, D R; Janouschek, H

Bias in HD-ISS staging introduced by the FreeSurfer cross-sectional stream: Insights from the Huntington's Disease Young Adult Study (HD-YAS)

FreeSurfer横断面研究引入的HD-ISS分期偏差:来自亨廷顿病青年成人研究(HD-YAS)的启示

Knights, Harry; Coleman, Annabelle; Farag, Mena; Leocadi, Michela; Murphy, Michael; Fayer, Kate; Thackeray, Olivia; Langbehn, Douglas; Hobbs, Nicola; Tabrizi, Sarah J; Scahill, Rachael I

Lack of Evidence for Kynurenine Pathway Dysfunction in Huntington's Disease: CSF and Plasma Analyses from the HDClarity Study

HDClarity 研究的脑脊液和血浆分析表明,亨廷顿病中犬尿氨酸通路功能障碍的证据不足

Khetarpal, Vinod; Herbst, Todd; Dominguez, Celia; Munoz-Sanjuan, Ignacio; Sampaio, Cristina; Marks, Bryan; Miller, Dennis L; Farnham, James; Ledvina, Aaron; Anglehart, Hannah; Rehmani, Imran; LaFayette, Amber; Spridco, Natasha; Langbehn, Douglas; Wild, Edward J; Pacifici, Robert

SPRING, an effective and reliable framework for image reconstruction in single-particle Coherent Diffraction Imaging

SPRING,一种用于单粒子相干衍射成像图像重建的有效可靠的框架

Colombo, Alessandro; Sauppe, Mario; Al Haddad, Andre; Ayyer, Kartik; Babayan, Morsal; Boll, Rebecca; Dagar, Ritika; Dold, Simon; Fennel, Thomas; Hecht, Linos; Knopp, Gregor; Kolatzki, Katharina; Langbehn, Bruno; Maia, Filipe R N C; Mall, Abhishek; Mazumder, Parichita; Mazza, Tommaso; Ovcharenko, Yevheniy; Polat, Ihsan Caner; Raiser, Dirk; Schäfer-Zimmermann, Julian C; Schnorr, Kirsten; Schubert, Marie Louise; Sehati, Arezu; Sellberg, Jonas A; Senfftleben, Björn; Shen, Zhou; Sun, Zhibin; Svensson, Pamela H W; Tümmler, Paul; Usenko, Sergey; Ussling, Carl Frederic; Veteläinen, Onni; Wächter, Simon; Walsh, Noelle; Weitnauer, Alex V; You, Tong; Zuod, Maha; Meyer, Michael; Bostedt, Christoph; Galli, Davide E; Patanen, Minna; Rupp, Daniela

Cognition Disconnected: The Influence of Domain-General Cognition (g) in Lesion-Deficit Mapping

认知脱节:领域通用认知(g)在损伤-缺陷映射中的影响

Sozer, Lara; Griffis, Joseph; Langbehn, Kathleen; Bruss, Joel; Olafson, Emily; Manzel, Kenneth; Corbetta, Maurizio; Tranel, Daniel; Boes, Aaron D; Bowren, Mark Jr

Acute post-stroke cognitive test performance predicts one-year functional independence

急性中风后认知测试表现可预测一年后的功能独立性

Romanowski, Alan; Langbehn, Kathleen; Corbetta, Maurizio; Tranel, Daniel; Boes, Aaron D; Bowren, Mark Jr

Increased frequency of repeat expansion mutations across different populations

不同人群中重复序列扩增突变的频率增加

Ibañez, Kristina; Jadhav, Bharati; Zanovello, Matteo; Gagliardi, Delia; Clarkson, Christopher; Facchini, Stefano; Garg, Paras; Martin-Trujillo, Alejandro; Gies, Scott J; Galassi Deforie, Valentina; Dalmia, Anupriya; Hensman Moss, Davina J; Vandrovcova, Jana; Rocca, Clarissa; Moutsianas, Loukas; Marini-Bettolo, Chiara; Walker, Helen; Turner, Chris; Shoai, Maryam; Long, Jeffrey D; Fratta, Pietro; Langbehn, Douglas R; Tabrizi, Sarah J; Caulfield, Mark J; Cortese, Andrea; Escott-Price, Valentina; Hardy, John; Houlden, Henry; Sharp, Andrew J; Tucci, Arianna