Mitsuyoshi Azuma相关文献与解析，生知库 | 链接生命科学的每一步

Activation of Cytosolic Calpain, Not Caspase, Is Underlying Mechanism for Hypoxic RGC Damage in Human Retinal Explants

细胞浆钙蛋白酶（而非胱天蛋白酶）的激活是人类视网膜外植体缺氧 RGC 损伤的潜在机制

期刊:Investigative Ophthalmology & Visual Science

影响因子:5

doi:10.1167/iovs.61.13.13

Momoko Kobayashi-Otsugu, Kana Orihara, Emi Nakajima, Thomas R Shearer, Mitsuyoshi Azuma

NFE2L2 activator RS9 protects against corneal epithelial cell damage in dry eye models

NFE2L2 激活剂 RS9 可防止干眼症模型中的角膜上皮细胞损伤

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0229421

Yuka Matsuda, Mamiko Machida, Yasuhiro Nakagami, Takeshi Nakajima, Mitsuyoshi Azuma

Cell-Permeable Calpain Inhibitor SJA6017 Provides Functional Protection to Spinal Motoneurons Exposed to MPP

细胞通透性钙蛋白酶抑制剂 SJA6017 为暴露于 MPP 的脊髓运动神经元提供功能保护

期刊:Neurotoxicity Research

影响因子:2.9

doi:10.1007/s12640-020-00264-3

Supriti Samantaray, Varduhi H Knaryan, Angelo M Del Re, John J Woodward, Donald C Shields, Mitsuyoshi Azuma, Jun Inoue, Swapan K Ray, Naren L Banik

Neuron-microglia interaction induced bi-directional cytotoxicity associated with calpain activation

神经元-小胶质细胞相互作用诱导与钙蛋白酶激活相关的双向细胞毒性

期刊:Journal of Neurochemistry

影响因子:4.2

doi:10.1111/jnc.13774

Maria Podbielska, Arabinda Das, Amena W Smith, Ashok Chauhan, Swapan K Ray, Jun Inoue, Mitsuyoshi Azuma, Kenkichi Nozaki, Edward L Hogan, Naren L Banik

Calpain inhibition reduces structural and functional impairment of retinal ganglion cells in experimental optic neuritis

钙蛋白酶抑制可减轻实验性视神经炎中视网膜神经节细胞的结构和功能损伤

期刊:Journal of Neurochemistry

影响因子:4.2

doi:10.1111/jnc.13770

Amena W Smith, Baerbel Rohrer, Lee Wheless, Supriti Samantaray, Swapan K Ray, Jun Inoue, Mitsuyoshi Azuma, Naren L Banik

Effects of a novel orally administered calpain inhibitor SNJ-1945 on immunomodulation and neurodegeneration in a murine model of multiple sclerosis

新型口服钙蛋白酶抑制剂 SNJ-1945 对多发性硬化症小鼠模型的免疫调节和神经退行性的影响

期刊:Journal of Neurochemistry

影响因子:4.2

doi:10.1111/jnc.12659

Nicole Trager, Amena Smith, Gerald Wallace Iv, Mitsuyoshi Azuma, Jun Inoue, Craig Beeson, Azizul Haque, Naren L Banik

SNJ-1945, a calpain inhibitor, protects SH-SY5Y cells against MPP(+) and rotenone

SNJ-1945 是一种钙蛋白酶抑制剂，可保护 SH-SY5Y 细胞免受 MPP(+) 和鱼藤酮的侵害

期刊:Journal of Neurochemistry

影响因子:4.2

doi:10.1111/jnc.12629

Varduhi H Knaryan, Supriti Samantaray, Sookyoung Park, Mitsuyoshi Azuma, Jun Inoue, Naren L Banik

Calpain, not caspase, is the causative protease for hypoxic damage in cultured monkey retinal cells

钙蛋白酶，而不是胱天蛋白酶，是培养的猴视网膜细胞中缺氧损伤的致病蛋白酶

期刊:Investigative Ophthalmology & Visual Science

影响因子:5

doi:10.1167/iovs.11-7497

Emi Nakajima, Katherine B Hammond, Jennifer L Rosales, Thomas R Shearer, Mitsuyoshi Azuma

Human and monkey lenses cultured with calcium ionophore form alphaB-crystallin lacking the C-terminal lysine, a prominent feature of some human cataracts

人类和猴子的晶状体与钙离子载体培养，形成缺乏 C 端赖氨酸的 alphaB-晶体蛋白，这是某些人类白内障的显著特征

期刊:Investigative Ophthalmology & Visual Science

影响因子:5

doi:10.1167/iovs.09-4015

Emi Nakajima, Larry L David, Michael A Riviere, Mitsuyoshi Azuma, Thomas R Shearer

Tear miRNA expression analysis reveals miR-203 as a potential regulator of corneal epithelial cells

泪液 miRNA 表达分析表明 miR-203 可能是角膜上皮细胞的潜在调节因子。

Activation of Cytosolic Calpain, Not Caspase, Is Underlying Mechanism for Hypoxic RGC Damage in Human Retinal Explants

细胞浆钙蛋白酶（而非胱天蛋白酶）的激活是人类视网膜外植体缺氧 RGC 损伤的潜在机制

NFE2L2 activator RS9 protects against corneal epithelial cell damage in dry eye models

NFE2L2 激活剂 RS9 可防止干眼症模型中的角膜上皮细胞损伤

Cell-Permeable Calpain Inhibitor SJA6017 Provides Functional Protection to Spinal Motoneurons Exposed to MPP

细胞通透性钙蛋白酶抑制剂 SJA6017 为暴露于 MPP 的脊髓运动神经元提供功能保护

Neuron-microglia interaction induced bi-directional cytotoxicity associated with calpain activation

神经元-小胶质细胞相互作用诱导与钙蛋白酶激活相关的双向细胞毒性

Calpain inhibition reduces structural and functional impairment of retinal ganglion cells in experimental optic neuritis

钙蛋白酶抑制可减轻实验性视神经炎中视网膜神经节细胞的结构和功能损伤

Effects of a novel orally administered calpain inhibitor SNJ-1945 on immunomodulation and neurodegeneration in a murine model of multiple sclerosis

新型口服钙蛋白酶抑制剂 SNJ-1945 对多发性硬化症小鼠模型的免疫调节和神经退行性的影响

SNJ-1945, a calpain inhibitor, protects SH-SY5Y cells against MPP(+) and rotenone

SNJ-1945 是一种钙蛋白酶抑制剂，可保护 SH-SY5Y 细胞免受 MPP(+) 和鱼藤酮的侵害

Calpain, not caspase, is the causative protease for hypoxic damage in cultured monkey retinal cells

钙蛋白酶，而不是胱天蛋白酶，是培养的猴视网膜细胞中缺氧损伤的致病蛋白酶

Human and monkey lenses cultured with calcium ionophore form alphaB-crystallin lacking the C-terminal lysine, a prominent feature of some human cataracts

人类和猴子的晶状体与钙离子载体培养，形成缺乏 C 端赖氨酸的 alphaB-晶体蛋白，这是某些人类白内障的显著特征