日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A functional aged human iPSC-cortical neuron model recapitulates Alzheimer's disease, senescence, and the response to therapeutics

功能性老年人类 iPSC 皮质神经元模型重现了阿尔茨海默病、衰老和对治疗的反应

Leandro H Gallo, Nesar Akanda, Kaveena Autar, Aakash Patel, Ian Cox, Haley A Powell, Marcella Grillo, Natali Barakat, Dave Morgan, Xiufang Guo, James J Hickman

Establishment of a Serum-Free Human iPSC-Derived Model of Peripheral Myelination

建立无血清人类 iPSC 衍生外周髓鞘形成模型

Aakash Patel, Marnie Williams, Kenneth Hawkins, Leandro Gallo, Marcella Grillo, Nesar Akanda, Xiufang Guo, Stephen Lambert, James J Hickman

Validation of a functional human AD model with four AD therapeutics utilizing patterned ipsc-derived cortical neurons integrated with microelectrode arrays

利用与微电极阵列集成的模式化 ipsc 衍生皮质神经元,验证具有四种 AD 疗法的功能性人类 AD 模型

Julbert Caneus #, Kaveena Autar #, Nesar Akanda, Marcella Grillo, Christopher J Long, Max Jackson, Sarah Lindquist, Xiufang Guo, Dave Morgan, James J Hickman

Validation of a functional human AD model with four AD therapeutics utilizing patterned iPSC-derived cortical neurons integrated with microelectrode arrays

利用与微电极阵列集成的模式化 iPSC 衍生皮质神经元,验证具有四种 AD 疗法的功能性人类 AD 模型

Julbert Caneus, Kaveena Autar, Nesar Akanda, Marcella Grillo, Chris Long, Max Jackson, Sarah Lindquist, Xiufang Guo, Dave Morgan, James J Hickman

Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a pain model for analgesic drug testing

开发功能性人类诱导多能干细胞衍生的伤害感受器 MEA 系统作为镇痛药物测试的疼痛模型

Siddharth Nimbalkar, Xiufang Guo, Alisha Colón, Max Jackson, Nesar Akanda, Aakash Patel, Marcella Grillo, James J Hickman

An induced pluripotent stem cell-derived NMJ platform for study of the NGLY1-Congenital Disorder of Deglycosylation

诱导性多能干细胞衍生的 NMJ 平台,用于研究 NGLY1-先天性去糖基化障碍

Trevor Sasserath, Ashley L Robertson, Roxana Mendez, Tristan T Hays, Ethan Smith, Helena Cooper, Nesar Akanda, John W Rumsey, Xiufang Guo, Atena Farkhondeh, Manisha Pradhan, Karsten Baumgaertel, Matthew Might, Steven Rodems, Wei Zheng, James J Hickman

A human induced pluripotent stem cell-derived cortical neuron human-on-a chip system to study Aβ42 and tau-induced pathophysiological effects on long-term potentiation

人类诱导性多能干细胞衍生的皮质神经元人芯片系统,用于研究 Aβ42 和 tau 诱导的长期增强病理生理影响

Julbert Caneus, Nesar Akanda, John W Rumsey, Xiufang Guo, Max Jackson, Christopher J Long, Frank Sommerhage, Sanya Georgieva, Nicholas M Kanaan, David Morgan, James J Hickman

Tissue engineering the mechanosensory circuit of the stretch reflex arc with human stem cells: Sensory neuron innervation of intrafusal muscle fibers

利用人类干细胞组织工程构建拉伸反射弧的机械感觉回路:感觉神经元对肌梭内肌纤维的支配

Xiufang Guo, Alisha Colon, Nesar Akanda, Severo Spradling, Maria Stancescu, Candace Martin, James J Hickman

Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs

在由四个器官组成的功能性人体体外系统中进行多器官毒性演示

Carlota Oleaga ,Catia Bernabini ,Alec S T Smith ,Balaji Srinivasan ,Max Jackson ,William McLamb ,Vivien Platt ,Richard Bridges ,Yunqing Cai ,Navaneetha Santhanam ,Bonnie Berry ,Sarah Najjar ,Nesar Akanda ,Xiufang Guo ,Candace Martin ,Gail Ekman ,Mandy B Esch ,Jessica Langer ,Gladys Ouedraogo ,Jose Cotovio ,Lionel Breton ,Michael L Shuler ,James J Hickman

Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems

在特定培养系统中对人类诱导多能干细胞衍生的神经元 (iCell Neurons) 进行形态和功能表征

Bonnie J Berry, Nesar Akanda, Alec S T Smith, Christopher J Long, Mark T Schnepper, Xiufang Guo, James J Hickman