日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification and characterization of the functional LolB ortholog in Bacteroides

拟杆菌属中功能性 LolB 直系同源基因的鉴定和表征

Armbruster, Krista M; Trickannad, Rhea; Scott, Nichollas E; Pudlo, Nicholas A; Wotring, Jesse W; Martens, Eric C; Sexton, Jonathan Z; Koropatkin, Nicole M

Salmonella Typhi asparaginase-dependent activation of GCN2 promotes bacterial killing in murine macrophages

伤寒沙门氏菌天冬酰胺酶依赖性GCN2激活促进小鼠巨噬细胞杀灭细菌

Powers, Zachary M; McFadden, Michael J; Lee, Gi Young; Schultz, Tracey; Jorge, Luiza A Castro; Edwards, Daniel F; Sanchez-Paiva, Simon; Sexton, Jonathan Z; Spindler, Katherine R; Song, Jeongmin; O'Riordan, Mary X

Neutrophils secrete exosome-associated DNA to resolve sterile acute inflammation

中性粒细胞分泌外泌体相关DNA以消除无菌性急性炎症

Arya, Subhash B; Collie, Samuel P; Xu, Yang; Fernandez, Martin; Sexton, Jonathan Z; Mosalaganti, Shyamal; Coulombe, Pierre A; Parent, Carole A

Large-scale transcriptome mining enables macrocyclic diversification and improved bioactivity of the stephanotic acid scaffold.

大规模转录组挖掘能够实现大环多样化,并提高斯蒂芬酸骨架的生物活性

Wang Xiaofeng, Shafiq Khadija, Ousley Derrick A, Chigumba Desnor N, Davis Dulciana, McDonough Kali M, Mydy Lisa S, Sexton Jonathan Z, Kersten Roland D

IRE1α promotes phagosomal calcium flux to enhance macrophage fungicidal activity.

IRE1α促进吞噬体钙流,从而增强巨噬细胞的杀真菌活性

McFadden Michael J, Reynolds Mack B, Michmerhuizen Britton C, Ólafsson Einar B, Marshall Sofia M, Davis Faith Anderson, Schultz Tracey L, Iwawaki Takao, Sexton Jonathan Z, O'Riordan Mary X D, O'Meara Teresa R

A scalable long-term in vitro model of human colonic epithelium with continuous barrier function

具有持续屏障功能的、可扩展的人类结肠上皮长期体外模型

Cuttitta, Ashley J; Meyer, Sophia R; Frum, Tristan; Gunuguntla, Bhargavasai; Wu, Angeline; Huang, Sha; Morgan, Jack; Dame, Michael K; Sexton, Jonathan Z; Spence, Jason R

Phenotypic Screening Coupled with AI-Driven Target Deconvolution Identifies α-Terthienyl as a Dual DPP-IV/HSD17β13 Modulator with Efficacy in a Mouse Model of MASLD

表型筛选结合人工智能驱动的靶点解卷积,鉴定出α-三噻吩是一种双重DPP-IV/HSD17β13调节剂,在MASLD小鼠模型中具有疗效。

Hoegeman, Kathryn M; Wotring, Jesse W; Fursmidt, Reid; Gaetz, Jedidiah; Khalil, Ehab M; Selinger, Douglas W; Kovalenko, Ilya; Schultz, Tracey L; McCarty, Sean M; O'Meara, Matthew J; Clasby, Martin C; Sexton, Jonathan Z

Identification and characterization of the lipoprotein N-acyltransferase in Bacteroides

拟杆菌中脂蛋白N-酰基转移酶的鉴定和表征

Armbruster, Krista M; Jiang, Jiawen; Sartorio, Mariana G; Scott, Nichollas E; Peterson, Jenna M; Sexton, Jonathan Z; Feldman, Mario F; Koropatkin, Nicole M

High-Throughput Methods for the Discovery of Small Molecule Modulators of Pancreatic Beta-Cell Function and Regeneration

用于发现胰岛β细胞功能和再生小分子调节剂的高通量方法

McCarty, Sean M; Clasby, Martin C; Sexton, Jonathan Z

Identification and Characterization of the Lipoprotein N-acyltransferase in Bacteroides

拟杆菌脂蛋白N-酰基转移酶的鉴定和表征

Armbruster, Krista M; Jiang, Jiawen; Sartorio, Mariana G; Scott, Nichollas E; Peterson, Jenna M; Sexton, Jonathan Z; Feldman, Mario F; Koropatkin, Nicole M