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巨噬细胞胃口有多大,细胞核说了算

巨噬细胞是组织清道夫,天天吞凋亡细胞。但细胞质就那么大,越吞越挤,它靠什么一直吃下去?爱丁堡大学在果蝇活体里拍到:吞进去的凋亡小体会把细胞核压得凹陷变形——原来吞噬不只是"吃",还是一场机械负担。更妙的是核的应对:吞噬活动会让核纤层蛋白Lamin B水平上升,相当于给核加钢筋。而一旦沉默Lamin B或LI

【文献解析】Atlantic salmon skin and corneal keratocytes exhibit phagocytic activity and express immune-related genes upon bacterial exposure

1. 领域背景与文献引入文献英文标题:Atlantic salmon skin and corneal keratocytes exhibit phagocytic activity and express immune-related genes upon bacterial exposure;发表期刊:BMC Veterinary Research;影响因子:2.5(2023年);研究领域:水产动物免疫学,鱼类黏膜免疫。水产养殖产业中,大西洋鲑等养殖鱼类

Phagocytosis influences the intracellular survival of Mycobacterium smegmatis via the endoplasmic re

1. 领域背景与文献引入文献英文标题:Phagocytosis influences the intracellular survival of Mycobacterium smegmatis via the endoplasmic reticulum stress response;发表期刊:Cell & Bioscience;影响因子:未公开;研究领域:非结核分枝杆菌感染与宿主天然免疫非结核分枝杆菌(NTM)是除结核分枝杆菌(Mtb)和麻