【文献解析】勘误:前列腺癌细胞中Wnt抑制因子1的恢复与肿瘤生长抑制、细胞迁移侵袭能力降低及上皮间质转化逆转相关
1. 领域背景与文献文献英文标题:Correction: The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition;发表期刊:Molecular Cancer;影响因子:未明确
【文献解析】全身免疫抑制限制胰腺癌中NK细胞治疗的疗效
1. 领域背景与文献文献英文标题:Systemic immunosuppression limits NK cell therapy efficacy in pancreatic cancer;发表期刊:Molecular Cancer;影响因子:未公开;研究领域:胰腺癌免疫治疗、NK细胞功能调控胰腺癌是临床恶性程度极高的消化系统肿瘤,其5年生存率不足10%,传统治疗手段疗效有限,免疫治疗为其带来新的
【文献解析】Autophagy in cancer — functional plasticity, therapeutic paradox, and the road to precision modulation: a comprehensive review
1. 领域背景与文献文献英文标题:Autophagy in cancer — functional plasticity, therapeutic paradox, and the road to precision modulation: a comprehensive review发表期刊:Molecular Cancer;影响因子:未公开(领域共识:该期刊为肿瘤学领域顶级综述类期刊,近年影响因子稳定在30+区间);研究领域:肿瘤学(自噬与
【文献解析】通过转录组RNA-seq评估炎症相关信号通路在大鼠呼吸机诱导膈肌功能障碍中的作用
1. 领域背景与文献文献英文标题:Assessment of the role of inflammation-linked signaling pathways in ventilator-induced diaphragmatic dysfunction in rats by transcriptome RNA-seq;发表期刊:BMC Molecular and Cell Biology;影响因子:未公开;研究领域:重症医学/呼吸病学(呼吸机诱导膈肌功能障碍分子机制研究
【文献解析】脂质体药物递送在肺癌治疗中的进展、挑战与未来展望
1. 领域背景与文献文献英文标题:Liposomal drug delivery for lung cancer therapy: progress, challenges, and future perspectives;发表期刊:Mol Cancer;影响因子:未公开;研究领域:肿瘤学(肺癌靶向药物递送)肺癌是全球范围内导致癌症相关死亡的首要原因,传统化疗药物因靶向性差、全身毒副作用显著、多药耐药等问
【文献解析】打破骨转移中的免疫“冷微环境”:多维交织调控网络的核心机制与精准突破策略
1. 领域背景与文献文献英文标题:Breaking the immune “cold niche” in bone metastasis: core mechanisms of the multidimensional interwoven regulatory network and precision breakthrough strategies;发表期刊:Mol Cancer;影响因子:未公开;研究领域:肿瘤学-骨转移免疫治疗领域共识:骨转移是晚期恶性肿瘤的标
【文献解析】癌旁肝细胞YTHDF2通过CX3CL1介导的CD8+T细胞招募调控化疗诱导的抗肿瘤免疫反应
1. 领域背景与文献文献英文标题:YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment;发表期刊:Molecular Cancer;影响因子:41.444(2023年);研究领域:肿瘤学(肝癌免疫治疗与RNA修饰)肝癌是全球范围内常见的恶性肿瘤,
【文献解析】重编程胰腺导管腺癌微环境:新型整合素靶向毒素ProAgio增强化疗疗效
1. 领域背景与文献文献英文标题:Reprogramming the pancreatic ductal adenocarcinoma microenvironment: a novel integrin-targeted cytotoxin, ProAgio, potentiates chemotherapy;发表期刊:Mol Cancer;影响因子:未公开;研究领域:肿瘤学(胰腺导管腺癌)领域共识:胰腺导管腺癌(PDAC)是恶性程度最高的消化系统肿
【文献解析】circNFIB1通过miR-486-5p/PIK3R1/VEGF-C轴抑制胰腺癌淋巴管生成和淋巴转移
1. 领域背景与文献文献英文标题:Correction: circNFIB1 inhibits lymphangiogenesis and lymphatic metastasis via the miR-486-5p/PIK3R1/VEGF-C axis in pancreatic cancer;发表期刊:Molecular Cancer;影响因子:未公开;研究领域:胰腺癌分子生物学、肿瘤淋巴转移机制胰腺癌是恶性程度极高的消化系统肿瘤,领域共识:
【文献解析】Bmi-1促进乳腺癌侵袭转移且其高表达与疾病晚期相关
1. 领域背景与文献文献英文标题:Correction: Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer;发表期刊:Molecular Cancer(缩写Mol Cancer);影响因子:未公开;研究领域:肿瘤学(乳腺癌分子机制与生物标志物)乳腺癌是全球女性群体中发