【文献解析】一线免疫联合治疗转移性透明细胞肾细胞癌的分子标志物:Meet-URO组对III期随机临床试验的系统评价
1. 领域背景与文献文献英文标题:Molecular biomarkers in metastatic clear cell renal cell carcinoma treated with first-line immune combinations: a systematic review of phase III randomized clinical trials by Meet-URO group;发表期刊:未明确;影响因子:未公开;研究领域:转移性透明细胞肾细胞癌一线免疫治
【文献解析】抗PD-1联合IFN-α1b加或不加安罗替尼一线治疗不可切除晚期黑色素瘤的疗效与安全性:一项真实世界队列研究
1. 领域背景与文献文献英文标题:Efficacy and safety of anti-PD-1 combined with IFN-α1b with or without anlotinib as the first-line therapy in patients with unresectable advanced melanoma: a real-world cohort study;发表期刊:Cancer Immunol Immunother;影响因子:未公开;研究领域:肿瘤学临床,晚期黑色
【文献解析】IOBRportal:用于肿瘤微环境与基因组景观多维解析的云集成平台
1. 领域背景与文献文献英文标题:IOBRportal: a cloud-based integrated platform for multidimensional decoding of tumor microenvironment and genomic landscapes;发表期刊:Cancer Immunol Immunother;影响因子:未公开;研究领域:肿瘤免疫生物信息学,免疫肿瘤学领域共识:批量转录组分析是免疫肿瘤学研究中解析肿
【文献解析】免疫检查点阻断可通过不依赖1型常规树突状细胞的方式促进原发肿瘤排斥且不获得免疫记忆
1. 领域背景与文献文献英文标题:Immune checkpoint blockade facilitates primary tumor rejection in a cDC1-independent manner without immunological memory acquisition;发表期刊:Cancer Immunol Immunother;影响因子:未公开;研究领域:肿瘤免疫治疗(免疫检查点阻断机制方向)。领域共识:免疫检查点阻断是目前
【文献解析】整合严重免疫相关不良事件预测模型与疗效生物标志物实现非小细胞肺癌免疫治疗精准分层:来自III期ORIENT-11研究的启示
1. 领域背景与文献文献英文标题:Integration of a severe immune-related adverse events predictive model with efficacy biomarkers enables precise stratification in NSCLC immunotherapy: insights from the phase 3 ORIENT-11 study;发表期刊:Cancer Immunol Immunother;影响因子:未公开;研究领域:非小细胞肺
【文献解析】静止与衰老中生长停滞的阈值调控:对衰老与癌症细胞命运可塑性的启示
1. 领域背景与文献文献英文标题:Threshold control of growth arrest in quiescence and senescence: implications for cell fate plasticity in aging and cancer;发表期刊:Molecular Cancer;影响因子:未公开;研究领域:衰老与肿瘤生物学,细胞命运调控细分领域。领域共识:长期以来,细胞衰老与静止的分类研究是衰老
【文献解析】小细胞肺癌中细胞稳态与免疫控制依赖于可靶向的无义介导降解通路
1. 领域背景与文献文献英文标题:A targetable dependency on nonsense-mediated decay for cellular homeostasis and immune control in small cell lung cancer;发表期刊:Molecular Cancer;影响因子:未公开;研究领域:小细胞肺癌靶向治疗与肿瘤免疫治疗领域共识:小细胞肺癌(SCLC)是侵袭性最强的恶性肿瘤之一,具有
【文献解析】Retraction Note: Human epididymis protein 4 in association with Annexin II promotes invasion and metastasis of ovarian cancer cells
1. 领域背景与文献文献英文标题:Retraction Note: Human epididymis protein 4 in association with Annexin II promotes invasion and metastasis of ovarian cancer cells;发表期刊:Molecular Cancer;影响因子:文献未明确提供原文章发表时该期刊影响因子,当前该期刊影响因子为41.0;研究领域:肿瘤学,卵巢癌侵袭转
【文献解析】肺神经内分泌肿瘤和超类癌的深度分子谱分析
1. 领域背景与文献文献英文标题:Deep molecular profiling of lung neuroendocrine tumours and supra-carcinoids。发表期刊:未明确;影响因子:未公开;研究领域:肺神经内分泌肿瘤分子分型。领域共识:肺神经内分泌肿瘤全球发病率呈快速上升趋势,但其病因尚不明确,手术以外的治疗选择十分有限。当前世界卫生组织基于核
【文献解析】Correction: Multimodal sequencing identifies synergistic mechanisms driving resistance to neoadjuvant nivolumab treatment in hepatocellular carcinoma
1. 领域背景与文献文献英文标题:Correction: Multimodal sequencing identifies synergistic mechanisms driving resistance to neoadjuvant nivolumab treatment in hepatocellular carcinoma;发表期刊:Molecular Cancer;影响因子:未公开;研究领域:肿瘤学-肝细胞癌免疫治疗。领域共识:肝细胞癌是全球高发的恶性肿瘤