【文献解析】肝类器官:抗肝纤维化机制研究与药物筛选的新型平台
1. 领域背景与文献文献英文标题:Liver organoids: a novel platform for mechanistic research and drug screening in anti-liver fibrosis;发表期刊:Stem Cell Research & Therapy;影响因子:未公开;研究领域:肝脏疾病(肝纤维化)、三维类器官技术、转化医学与再生医学肝纤维化是各类慢性肝病进展至肝硬化、肝癌
【文献解析】B细胞在成骨稳态中的重要性
1. 领域背景与文献文献英文标题:The importance of B cells for osteogenic homeostasis;发表期刊:未公开;影响因子:未公开;研究领域:骨免疫学与再生医学骨免疫学是聚焦免疫系统与骨骼系统相互作用的新兴交叉学科,其发展关键节点包括早期发现先天免疫细胞可通过诱导成骨前体细胞向破骨细胞分化,参与骨损伤后坏死组织
【文献解析】ADGRV1的结构特征与疾病相关功能:信号机制视角
1. 领域背景与文献文献英文标题:Structural features and disease-associated functions of ADGRV1: insights from signaling mechanisms;发表期刊:Cell Communication and Signaling;影响因子:未公开;研究领域:细胞信号转导、神经退行性疾病、肿瘤学、遗传性听觉-视觉疾病交叉领域领域共识:黏附G蛋白偶联受体(aGP
【文献解析】肺炎衣原体调控动脉粥样硬化的多阶段信号网络:从内皮功能障碍到斑块易损性
1. 领域背景与文献文献英文标题:Chlamydia pneumoniae orchestrates a multi-stage signaling network in atherosclerosis: from endothelial dysfunction to plaque vulnerability;发表期刊:Cell Communication and Signaling;影响因子:未公开;研究领域:心血管病学-感染与动脉粥样硬化分子机制动脉粥样硬化是全球心
【文献解析】急性缺血性卒中后TREM2通过AKT-PFKFB2介导的糖酵解重编程调控单核细胞来源巨噬细胞对凋亡神经元的持续吞噬作用
1. 领域背景与文献文献英文标题:TREM2 regulates continual efferocytosis of apoptotic neurons by monocyte-derived macrophages via AKT-PFKFB2-mediated glycolytic reprogramming after acute ischemic stroke;发表期刊:Cell Communication and Signaling;影响因子:未公开;研究领域:神经科学-急性缺血性卒中免疫
【文献解析】PIEZO2在神经病理性疼痛中的双重作用:介导外周敏化与机械负荷诱导的镇痛效应
1. 领域背景与文献文献英文标题:A dual role of PIEZO2 in neuropathic pain: driving peripheral sensitization and enabling mechanical loading-induced analgesia发表期刊:Cell Communication and Signaling;影响因子:8.9(2024);研究领域:神经科学(疼痛医学方向)神经病理性疼痛是临床常见的难治性慢性疼痛类型
【文献解析】Correction: Novel recombinant protein PK5-Gal-3C enhances the anti-tumor activity of T cells via binding with TRPV2
1. 领域背景与文献文献英文标题:Correction: Novel recombinant protein PK5-Gal-3C enhances the anti-tumor activity of T cells via binding with TRPV2;发表期刊:Cancer Immunology, Immunotherapy;影响因子:未公开获取;研究领域:肿瘤免疫治疗、T细胞功能调控肿瘤免疫治疗是当前肿瘤学研究的核心热点之一,尤其是
【文献解析】勘误:双模态成像实现原位胶质瘤脑室内CAR-T治疗的纵向生物分布分析
1. 领域背景与文献文献英文标题:Correction: Dual-modality imaging enables longitudinal biodistribution profiling of intracerebroventricular CAR-T therapy in orthotopic glioma;发表期刊:Cancer Immunology, Immunotherapy;影响因子:未公开;研究领域:神经肿瘤学(胶质瘤免疫治疗与分子成像)神经胶质瘤是中枢
【文献解析】微波消融联合抗LAG-3治疗通过调控CXCL10/CXCR3介导的CD8+T细胞活化增强肝癌小鼠抗肿瘤免疫
1. 领域背景与文献文献英文标题:Microwave ablation combined with anti-LAG-3 therapy enhances anti-tumor immunity in hepatocellular carcinoma mice by regulating CXCL10/CXCR3-mediated CD8+ T cell activation;发表期刊:Cancer Immunol Immunother;影响因子:未公开;研究领域:肿瘤学-肝细胞癌免疫治疗领域共识
【文献解析】基于免疫治疗响应的晚期肾细胞癌患者肿瘤免疫微环境基因表达分析(Meet-URO 18 I-TME研究)
1. 领域背景与文献文献英文标题:Gene expression analyses of immune tumor microenvironment in advanced renal cell carcinoma patients based on response to immunotherapy (Meet-URO 18 I-TME study);发表期刊:Cancer Immunol Immunother;影响因子:未公开;研究领域:泌尿生殖系统肿瘤学、肿瘤免疫治疗、肿瘤免疫