【文献解析】同步放化疗后CD24/MUC16与Siglec-10/Siglec-9互作介导宫颈癌免疫逃逸及复发的机制研究
1. 领域背景与文献引入文献英文标题:CD24/MUC16 interact with Siglec-10/Siglec-9 to promote immune evasion and recurrence of cervical cancer after concurrent chemoradiotherapy;发表期刊:未公开;影响因子:未公开;研究领域:妇科肿瘤学(宫颈癌免疫治疗与复发机制)宫颈癌是全球女性生殖系统最常见的恶性肿瘤之
【文献解析】CD155双靶点增强ROR1-CAR-T细胞在卵巢癌中的疗效研究
1. 领域背景与文献引入文献英文标题:未提供;发表期刊:未明确;影响因子:未公开;研究领域:卵巢癌免疫治疗(CAR-T细胞治疗)卵巢癌是威胁女性健康的高发恶性肿瘤,因起病隐匿且缺乏有效早期筛查手段,约70%患者确诊时已处于晚期阶段。尽管以铂类化疗为基础,联合PARP抑制剂或抗血管生成药物的维持治疗可延长患者无进展生
【文献解析】Metabolic syndrome is associated with increased risk of clinically significant immune-related adverse events in patients treated with immune checkpoint inhibitors
1. 领域背景与文献文献英文标题:Metabolic syndrome is associated with increased risk of clinically significant immune-related adverse events in patients treated with immune checkpoint inhibitors;发表期刊:未公开;影响因子:未公开;研究领域:肿瘤免疫治疗(免疫检查点抑制剂相关不良事件)肿瘤免疫治疗领域
【文献解析】Combining catgut embedding at the Zusanli acupoint with anti-PD-1 inhibitor enhances anti-tumor immunity by reprogramming the tumor microenvironment in lung cancer mouse models
1. 领域背景与文献引入文献英文标题:Combining catgut embedding at the Zusanli acupoint with anti-PD-1 inhibitor enhances anti-tumor immunity by reprogramming the tumor microenvironment in lung cancer mouse models;发表期刊:Journal of Immunological Methods;影响因子:未公开;研究领域:肺癌免疫治疗与针
【文献解析】全身免疫炎症指数与内脏-皮下脂肪比值预测CLDN18.2靶向CAR-T治疗晚期胃癌患者的细胞因子释放综合征严重程度
1. 领域背景与文献引入文献英文标题:Systemic immunoinflammatory index and visceral-to-subcutaneous fat ratio predict cytokine release syndrome severity in advanced gastric cancer patients treated with CLDN18.2-targeted CAR-T cells;发表期刊:未明确;影响因子:未公开;研究领域:肿瘤免疫治疗(胃癌CAR-T
【文献解析】低白蛋白血症通过损伤巨噬细胞精氨酸代谢驱动免疫检查点抑制剂耐药
1. 领域背景与文献文献英文标题:Hypoalbuminemia drives immune checkpoint inhibitor resistance via impairing macrophage arginine metabolism;发表期刊:未明确;影响因子:未公开;研究领域:肿瘤免疫治疗。肿瘤免疫治疗尤其是免疫检查点抑制剂(ICI)是肿瘤治疗领域的革命性突破,自2011年首个CTLA-4抑制剂获批以来
【文献解析】CAR-T细胞治疗实体瘤的前沿策略与挑战
1. 领域背景与文献文献英文标题:Advanced strategies to overcome barriers for CAR-T cell therapy in solid tumors;发表期刊:Journal of Cellular and Molecular Medicine;影响因子:5.295(2023年);研究领域:肿瘤免疫治疗(实体瘤CAR-T细胞治疗)领域共识:CAR-T细胞治疗自2017年首款产品获批以来,在血液系统恶性
【文献解析】免疫相关竞争性内源RNA(ImmCeRNA)的泛癌调控图谱及其临床转化价值
1. 领域背景与文献文献英文标题:Pan-cancer landscape of immune-related competing endogenous RNAs (ImmCeRNAs) and their implications for cancer immunotherapy;发表期刊:Cancer Immunology, Immunotherapy;影响因子:未公开;研究领域:肿瘤免疫治疗与非编码RNA调控肿瘤免疫治疗是癌症治疗领域的革命性突破,通过
【文献解析】CD25靶向近红外光免疫治疗联合瘤内注射白介素-15增强抗PD-1单抗在同源小鼠肿瘤模型中的疗效
1. 领域背景与文献文献英文标题:Combination of CD25-targeted near-infrared photoimmunotherapy and intratumoral interleukin-15 enhances anti-PD-1 monoclonal antibody therapy in syngeneic murine tumor models;发表期刊:Cancer Immunology, Immunotherapy;影响因子:6.9;研究领域:肿瘤免疫治疗肿瘤免疫治疗是
【文献解析】Long non-coding RNA RERE-AS1 acts as a promising prognostic biomarker and potential therapeutic target in breast cancer
1. 领域背景与文献文献英文标题:Long non-coding RNA RERE-AS1 acts as a promising prognostic biomarker and potential therapeutic target in breast cancer;发表期刊:未明确;影响因子:未公开;研究领域:乳腺癌分子生物学与肿瘤免疫治疗。乳腺癌是全球女性发病率最高的恶性肿瘤,其发病率持续上升,给患者家庭和社