Anti-CD45 antibody [EP322Y] (Ab40763)
CD45, PTPRC, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, T200, L-CA
详细信息
特异性
This antibody recognizes cytoplasmic domain of CD45.
背景信息
Anti-CD45 antibody [EP322Y] (ab40763) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB. Abcam's high quality manufacturing and validation processes ensure Anti-CD45 antibody [EP322Y] (ab40763) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-CD45 antibody [EP322Y] (ab40763) has 13 independent reviews from customers. Anti-CD45 antibody [EP322Y] (ab40763) specifically detects CD45 (UniProt ID: P08575; Molecular weight: 145kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EP322Y - ab214437. Antibody clone EP322Y is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, PE, PerCP, APC, Alexa Fluor ® 594 ( ab200315, ab200317, ab214501, ab220298, ab221245, ab303598 ). CD45 regulates immune cell signaling and is crucial in the development and function of immune cells, with alterations linked to various immunodeficiencies and autoimmune diseases. Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (119)
The functional and catalytic landscape of urease reveals a conserved target against Helicobacter pylori.
尿素酶的功能和催化特性揭示了其对抗幽门螺杆菌的保守靶点。
Novel approach for diabetic wound healing: adipose-derived mesenchymal stromal cells Exo@SPHydrogel combined with laser therapy.
糖尿病伤口愈合的新方法：脂肪来源间充质干细胞 Exo@SPHydrogel 与激光疗法相结合。
NR2F2/AGAP2 axis: regulating lipid synthesis to drive AML progression via AMPKα/ACC pathway.
NR2F2/AGAP2 轴：通过 AMPKα/ACC 通路调节脂质合成以驱动 AML 进展。
FBXO5 alleviates apical periodontitis by facilitating TP53 protein degradation.
FBXO5 通过促进 TP53 蛋白降解来缓解根尖周炎。
Ultrasound-guided intrarenal arterial injection promotes homing of MSCs and recovery of kidney in Adriamycin-induced nephropathy in rats.
超声引导下肾内动脉注射可促进间充质干细胞归巢，并促进阿霉素诱导的大鼠肾病肾脏的恢复。
Activation of TRPV4 to drive pyroptosis-dependent orthodontic tooth remodeling.
激活 TRPV4 以驱动依赖于细胞焦亡的正畸牙齿重塑。
GSTP1-modified exosomes derived from ADMSCs relieve LPS-induced acute lung injury.
源自 ADMSC 的 GSTP1 修饰的外泌体可缓解 LPS 诱导的急性肺损伤。
CTTN overexpression on circulating tumor cells promotes hepatocellular carcinoma recurrence via enhancing the proliferation and clonality of circulating tumor cells.
循环肿瘤细胞中 CTTN 的过度表达通过增强循环肿瘤细胞的增殖和克隆性促进肝细胞癌的复发。
Unfolded protein response kinase PERK supports survival and metastasis of circulating tumor cell clusters via SAM synthesis and H3K4me3-dependent PDGFB signaling.
未折叠蛋白反应激酶 PERK 通过 SAM 合成和 H3K4me3 依赖的 PDGFB 信号传导支持循环肿瘤细胞簇的存活和转移。
Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression
联合靶向不同细胞状态的胶质母细胞瘤干细胞可阻断恶性进展。
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